TY - JOUR
T1 - Progress in preeclampsia : the contribution of animal models
AU - Chau, Katrina
AU - Welsh, Mikala
AU - Makris, Angela
AU - Hennessy, Annemarie
PY - 2022
Y1 - 2022
N2 - Recent advances have been made in understanding the nature of placental dysfunction causing preeclampsia, and other hypertensive disorders of pregnancy. The contribution of animal studies in the understanding of the effects of inadequate placentation on blood pressure and other target organs will be explored in this review. This will include technical aspects of animal studies in pregnancy, as well as the translation of data regarding newly discovered pathological pathways, in particular the angiogenic pathway, into targets in clinical practice.
AB - Recent advances have been made in understanding the nature of placental dysfunction causing preeclampsia, and other hypertensive disorders of pregnancy. The contribution of animal studies in the understanding of the effects of inadequate placentation on blood pressure and other target organs will be explored in this review. This will include technical aspects of animal studies in pregnancy, as well as the translation of data regarding newly discovered pathological pathways, in particular the angiogenic pathway, into targets in clinical practice.
UR - https://hdl.handle.net/1959.7/uws:77798
U2 - 10.1038/s41371-021-00637-x
DO - 10.1038/s41371-021-00637-x
M3 - Article
SN - 0950-9240
VL - 36
SP - 705
EP - 710
JO - Journal of Human Hypertension
JF - Journal of Human Hypertension
IS - 8
ER -