TY - JOUR
T1 - Psychiatric and medical comorbidities of eating disorders : findings from a rapid review of the literature
AU - Hambleton, Ashlea
AU - Pepin, Genevieve
AU - Le, Anvi
AU - Maloney, Danielle
AU - Touyz, Stephen
AU - Maguire, Sarah
AU - National Eating Disorder Research Consortium, null
AU - Conti, Janet
AU - Hay, Phillipa
AU - Aouad, Phillip
AU - Barakat, Sarah
AU - Boakes, Robert
AU - Brennan, Leah
AU - Bryant, Emma
AU - Byrne, Susan
AU - Caldwell, Belinda
AU - Calvert, Shannon
AU - Carroll, Bronny
AU - Castle, David
AU - Caterson, Ian
AU - Chelius, Belinda
AU - Chiem, Lyn
AU - Clarke, Simon
AU - Crouch, Lexi
AU - Dammery, Genevieve
AU - Dzajkovski, Natasha
AU - Fardouly, Jasmine
AU - Felicia, Carmen
AU - Feneley, John
AU - Firriolo, Amber-Marie
AU - Foroughi, Nasim
AU - Fuller-Tyszkiewicz, Mathew
AU - Fursland, Anthea
AU - Gonzalez-Arce, Veronica
AU - Gouldthorp, Bethanie
AU - Grifn, Kelly
AU - Grifths, Scott
AU - Hannigan, Amy
AU - Hart, Mel
AU - Hart, Susan
AU - Hickie, Ian
AU - Kay-Lambkin, Francis
AU - King, Ross
AU - Kohn, Michael
AU - Koreshe, Eyza
AU - Krug, Isabel
AU - Linardon, Jake
AU - Long, Randall
AU - Long, Amanda
AU - Madden, Sloane
AU - et al, al
PY - 2022
Y1 - 2022
N2 - Background: Eating disorders (EDs) are potentially severe, complex, and life-threatening illnesses. The mortality rate of EDs is signifcantly elevated compared to other psychiatric conditions, primarily due to medical complications and suicide. The current rapid review aimed to summarise the literature and identify gaps in knowledge relating to any psychiatric and medical comorbidities of eating disorders. Methods: This paper forms part of a rapid review) series scoping the evidence base for the feld of EDs, conducted to inform the Australian National Eating Disorders Research and Translation Strategy 2021–2031, funded and released by the Australian Government. ScienceDirect, PubMed and Ovid/Medline were searched for English-language studies focused on the psychiatric and medical comorbidities of EDs, published between 2009 and 2021. High-level evidence such as meta-analyses, large population studies and Randomised Control Trials were prioritised. Results: A total of 202 studies were included in this review, with 58% pertaining to psychiatric comorbidities and 42% to medical comorbidities. For EDs in general, the most prevalent psychiatric comorbidities were anxiety (up to 62%), mood (up to 54%) and substance use and post-traumatic stress disorders (similar comorbidity rates up to 27%). The review also noted associations between specifc EDs and non-suicidal self-injury, personality disorders, and neurodevelopmental disorders. EDs were complicated by medical comorbidities across the neuroendocrine, skeletal, nutritional, gastrointestinal, dental, and reproductive systems. Medical comorbidities can precede, occur alongside or emerge as a complication of the ED. Conclusions: This review provides a thorough overview of the comorbid psychiatric and medical conditions cooccurring with EDs. High psychiatric and medical comorbidity rates were observed in people with EDs, with comorbidities contributing to increased ED symptom severity, maintenance of some ED behaviours, and poorer functioning as well as treatment outcomes. Early identifcation and management of psychiatric and medical comorbidities in people with an ED may improve response to treatment and overall outcomes.
AB - Background: Eating disorders (EDs) are potentially severe, complex, and life-threatening illnesses. The mortality rate of EDs is signifcantly elevated compared to other psychiatric conditions, primarily due to medical complications and suicide. The current rapid review aimed to summarise the literature and identify gaps in knowledge relating to any psychiatric and medical comorbidities of eating disorders. Methods: This paper forms part of a rapid review) series scoping the evidence base for the feld of EDs, conducted to inform the Australian National Eating Disorders Research and Translation Strategy 2021–2031, funded and released by the Australian Government. ScienceDirect, PubMed and Ovid/Medline were searched for English-language studies focused on the psychiatric and medical comorbidities of EDs, published between 2009 and 2021. High-level evidence such as meta-analyses, large population studies and Randomised Control Trials were prioritised. Results: A total of 202 studies were included in this review, with 58% pertaining to psychiatric comorbidities and 42% to medical comorbidities. For EDs in general, the most prevalent psychiatric comorbidities were anxiety (up to 62%), mood (up to 54%) and substance use and post-traumatic stress disorders (similar comorbidity rates up to 27%). The review also noted associations between specifc EDs and non-suicidal self-injury, personality disorders, and neurodevelopmental disorders. EDs were complicated by medical comorbidities across the neuroendocrine, skeletal, nutritional, gastrointestinal, dental, and reproductive systems. Medical comorbidities can precede, occur alongside or emerge as a complication of the ED. Conclusions: This review provides a thorough overview of the comorbid psychiatric and medical conditions cooccurring with EDs. High psychiatric and medical comorbidity rates were observed in people with EDs, with comorbidities contributing to increased ED symptom severity, maintenance of some ED behaviours, and poorer functioning as well as treatment outcomes. Early identifcation and management of psychiatric and medical comorbidities in people with an ED may improve response to treatment and overall outcomes.
UR - https://hdl.handle.net/1959.7/uws:67834
U2 - 10.1186/s40337-022-00654-2
DO - 10.1186/s40337-022-00654-2
M3 - Article
SN - 2050-2974
VL - 10
JO - Journal of Eating Disorders
JF - Journal of Eating Disorders
M1 - 132
ER -
