Abstract
In this chapter, the fundamentals of translational diffusion and PGSE NMR diffusion measurements and the solutions of the common artefacts in PGSE experiments (such as background gradients, huge solvent (e.g., water) signal, and thermal convection) are discussed and the practical issues of PGSE measurements (including sample preparation, selection of pulse sequences, and parameter settings) are considered; the fundamentals of the application of PGSE NMR to the study of ligand-macromolecule interactions and supramolecular assembly are examined.
Original language | English |
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Title of host publication | Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules |
Editors | Janice R. Aldrich-Wright |
Place of Publication | U.S. |
Publisher | Springer |
Pages | 159-185 |
Number of pages | 27 |
ISBN (Electronic) | 9783211990797 |
ISBN (Print) | 9783211094273 |
DOIs | |
Publication status | Published - 2011 |