Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

Joanna E. Harnett; Stephen P. Myers

doi:10.1038/s41598-020-58236-8

Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

Joanna E. Harnett, Stephen P. Myers

Western Sydney University

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 Â± 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 Â± 0.88, emotional 32.9 Â± 0.99, worries 39.8 Â± 0.79 and social 41 Â± 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.

Original language	English
Number of pages	5
Journal	Scientific Reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-58236-8
Publication status	Published - 2020

Open Access - Access Right Statement

Â© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Cre- ative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not per- mitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Access to Document

10.1038/s41598-020-58236-8

Cite this

@article{f1d828131f784f00bfa8e58ce7394f1d,

title = "Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet",

abstract = "People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 {\^A}± 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 {\^A}± 0.88, emotional 32.9 {\^A}± 0.99, worries 39.8 {\^A}± 0.79 and social 41 {\^A}± 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.",

author = "Harnett, {Joanna E.} and Myers, {Stephen P.}",

year = "2020",

doi = "10.1038/s41598-020-58236-8",

language = "English",

volume = "10",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

number = "1",

}

TY - JOUR

T1 - Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

AU - Harnett, Joanna E.

AU - Myers, Stephen P.

PY - 2020

Y1 - 2020

N2 - People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 Â± 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 Â± 0.88, emotional 32.9 Â± 0.99, worries 39.8 Â± 0.79 and social 41 Â± 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.

AB - People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 Â± 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 Â± 0.88, emotional 32.9 Â± 0.99, worries 39.8 Â± 0.79 and social 41 Â± 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.

UR - https://hdl.handle.net/1959.7/uws:64610

U2 - 10.1038/s41598-020-58236-8

DO - 10.1038/s41598-020-58236-8

M3 - Article

SN - 2045-2322

VL - 10

JO - Scientific Reports

JF - Scientific Reports

IS - 1

ER -

Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

Abstract

Open Access - Access Right Statement

Access to Document

Other files and links

Fingerprint

Cite this