Abstract
Kidney disease and high blood pressure are closely linked. Hypertension is multifactorial in origin and not previously considered a single gene disorder. However, although most people with high blood pressure do not have kidney disease, there have now been at least six single gene mutations linked to families with hypertension, all at sites of renal tubular proteins responsible for salt and water balance.1 These genotype studies both lead us to novel causes of hypertension, and provide a potent source of likely targets for treating hypertension.
| Original language | English |
|---|---|
| Journal | The Medical Journal of Australia |
| Publication status | Published - 2002 |
Keywords
- blood pressure
- xenografts
- homografts
- kidney disease
- chronic rejection
