TY - JOUR
T1 - Research priorities on physical-mental comorbidity in children and adolescents
T2 - an international consensus
AU - Jiang, Denan
AU - Zhou, Jiali
AU - Zhu, Yajie
AU - Abdin, Edimansyah
AU - Afifi, Tracie O.
AU - Andrade, Laura Helena S.G.
AU - Bendayan, Rebecca
AU - Berkelbach van der Sprenkel, Emma E.
AU - Bruffaerts, Ronny
AU - Catalá-López, Ferrán
AU - Colman, Ian
AU - Druss, Benjamin G.
AU - Duncan, Laura
AU - Farič, Nuša
AU - Felix, Erika
AU - Foster, Holly
AU - Lu, Shurong
AU - Mansour, Hassan
AU - Marrie, Ruth Ann
AU - Meade, Tanya
AU - Meherali, Salima
AU - Muntaner, Carles
AU - Nomura, Yoko
AU - Okuyama, Junko
AU - Rees, Susan J.
AU - Reid, Graham J.
AU - Schneiderman, Janet U.
AU - Stein, Dan J.
AU - Thielen, Frederick W.
AU - Tso, Wan Yee Winnie
AU - Oliveira Werneck, André
AU - Wu, Xiaoyan
AU - Rudan, Igor
AU - Song, Peige
PY - 2025/11
Y1 - 2025/11
N2 - Physical-mental comorbidity in children and adolescents is an emerging global health concern, yet research remains fragmented and lacks a coordinated agenda. We conducted a global priority setting exercise using the Child Health and Nutrition Research Initiative method. A total of 134 research ideas were scored by 45 experts against five criteria: answerability, effectiveness, potential for paradigm shift, potential for translation and implementation, and impact on equity. The highest-ranked priorities focused on treatment strategies, early intervention, reducing disparities in care, and the role of schools and communities in supporting health. Comparative analyses revealed both shared and context-specific needs across income settings. This is the first global consensus on research priorities for child and adolescent physical-mental comorbidity and offers a strategic roadmap to guide future research and policy.
AB - Physical-mental comorbidity in children and adolescents is an emerging global health concern, yet research remains fragmented and lacks a coordinated agenda. We conducted a global priority setting exercise using the Child Health and Nutrition Research Initiative method. A total of 134 research ideas were scored by 45 experts against five criteria: answerability, effectiveness, potential for paradigm shift, potential for translation and implementation, and impact on equity. The highest-ranked priorities focused on treatment strategies, early intervention, reducing disparities in care, and the role of schools and communities in supporting health. Comparative analyses revealed both shared and context-specific needs across income settings. This is the first global consensus on research priorities for child and adolescent physical-mental comorbidity and offers a strategic roadmap to guide future research and policy.
KW - Child and adolescent health
KW - Global health
KW - Physical-mental comorbidity
KW - Research prioritization
UR - http://www.scopus.com/inward/record.url?scp=105019212811&partnerID=8YFLogxK
U2 - 10.1016/j.eclinm.2025.103559
DO - 10.1016/j.eclinm.2025.103559
M3 - Article
AN - SCOPUS:105019212811
SN - 2589-5370
VL - 89
JO - EClinicalMedicine
JF - EClinicalMedicine
M1 - 103559
ER -