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Revolutionizing eye care: exploring the potential of microneedle drug delivery

  • Satish Rojekar
  • , Swapnali Parit
  • , Amol D. Gholap
  • , Ajit Manchare
  • , Sopan N. Nangare
  • , Navnath T. Hatvate
  • , Vrushabh V. Sugandhi
  • , Keshav Raj Paudel
  • , Rahul G. Ingle
  • Icahn School of Medicine at Mount Sinai
  • Institute of Chemical Technology
  • St. John Institute of Pharmacy and Research
  • H. R. Patel Institute of Pharmaceutical Education and Research
  • St. John's University
  • Centenary Institute
  • University of Technology Sydney
  • Datta Meghe Institute of Higher Education and Research

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)
4 Downloads (Pure)

Abstract

Microneedle technology revolutionizes ocular drug delivery by addressing challenges in treating ocular diseases. This review explores its potential impact, recent advancements, and clinical uses. This minimally invasive technique offers precise control of drug delivery to the eye, with various microneedle types showing the potential to penetrate barriers in the cornea and sclera, ensuring effective drug delivery. Recent advancements have improved safety and efficacy, offering sustained and controlled drug delivery for conditions like age-related macular degeneration and glaucoma. While promising, challenges such as regulatory barriers and long-term biocompatibility persist. Overcoming these through interdisciplinary research is crucial. Ultimately, microneedle drug delivery presents a revolutionary method with the potential to significantly enhance ocular disease treatment, marking a new era in eye care.
Original languageEnglish
Article number1398
Number of pages53
JournalPharmaceutics
Volume16
Issue number11
DOIs
Publication statusPublished - Nov 2024
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2024 by the authors.

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