Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Theerthankar Das; Prashant K. Sharma; Henk J. Busscher; Henny C. Van Der Mei; Bastiaan P. Krom

doi:10.1128/AEM.03119-09

Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Theerthankar Das
, Prashant K. Sharma
, Henk J. Busscher
, Henny C. Van Der Mei
, Bastiaan P. Krom

University of Groningen

Research output: Contribution to journal › Article › peer-review

274 Citations (Scopus)

Abstract

Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

Original language	English
Pages (from-to)	3405-3408
Number of pages	4
Journal	Applied and Environmental Microbiology,
Volume	76
Issue number	10
DOIs	https://doi.org/10.1128/AEM.03119-09
Publication status	Published - May 2010
Externally published	Yes

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10.1128/AEM.03119-09

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title = "Role of extracellular DNA in initial bacterial adhesion and surface aggregation",

abstract = "Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.",

author = "Theerthankar Das and Sharma, \{Prashant K.\} and Busscher, \{Henk J.\} and \{Van Der Mei\}, \{Henny C.\} and Krom, \{Bastiaan P.\}",

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AU - Sharma, Prashant K.

AU - Busscher, Henk J.

AU - Van Der Mei, Henny C.

AU - Krom, Bastiaan P.

PY - 2010/5

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AB - Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

UR - https://www.scopus.com/pages/publications/77952244823

U2 - 10.1128/AEM.03119-09

DO - 10.1128/AEM.03119-09

M3 - Article

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AN - SCOPUS:77952244823

SN - 0099-2240

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SP - 3405

EP - 3408

JO - Applied and Environmental Microbiology,

JF - Applied and Environmental Microbiology,

IS - 10

ER -

Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Abstract

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