TY - JOUR
T1 - Rome Foundation and international neurogastroenterology and motility societies’ consensus on idiopathic gastroparesis
AU - Schol, Jolien
AU - Huang, I. Hsuan
AU - Carbone, Florencia
AU - Fernandez, Luis Maria Bustos
AU - Gourcerol, Guillaume
AU - Ho, Vincent
AU - Kohn, Geoffrey
AU - Lacy, Brian E.
AU - Colombo, Aurelio Lopez
AU - Miwa, Hiroto
AU - Moshiree, Baha
AU - Nguyen, Linda
AU - O'Grady, Greg
AU - Siah, Kewin T.H.
AU - Stanghellini, Vincenzo
AU - Tack, Jan
N1 - Publisher Copyright:
© 2025 Elsevier Ltd
PY - 2025/1
Y1 - 2025/1
N2 - To establish a consensus on the definition and management of idiopathic gastroparesis, international experts (selected by neurogastroenterology and motility societies and initiated by the Rome Foundation) devised 144 statements using the Delphi method, with at least 80% agreement required. This consensus defined idiopathic gastroparesis as the presence of symptoms associated with delayed gastric emptying in the absence of mechanical obstruction. Nausea and vomiting were identified as cardinal symptoms. Frequently co-existing symptoms are early satiation and postprandial fullness. Diagnosis requires the presence of these symptoms alongside delayed gastric emptying, measured by a 4 h scintigraphy or gastric emptying breath test of a mixed composition meal in the absence of mechanical obstruction. Therapeutic options with proven efficacy were sparse. Dietary adjustments, nutritional support (per guidelines from the European Society for Clinical Nutrition and Metabolism for substantial weight loss or intractable vomiting), and opioid cessation were recommended by a consensus opinion. Antiemetic and prokinetic agents were also considered potentially beneficial. This consensus offers a global perspective on idiopathic gastroparesis.
AB - To establish a consensus on the definition and management of idiopathic gastroparesis, international experts (selected by neurogastroenterology and motility societies and initiated by the Rome Foundation) devised 144 statements using the Delphi method, with at least 80% agreement required. This consensus defined idiopathic gastroparesis as the presence of symptoms associated with delayed gastric emptying in the absence of mechanical obstruction. Nausea and vomiting were identified as cardinal symptoms. Frequently co-existing symptoms are early satiation and postprandial fullness. Diagnosis requires the presence of these symptoms alongside delayed gastric emptying, measured by a 4 h scintigraphy or gastric emptying breath test of a mixed composition meal in the absence of mechanical obstruction. Therapeutic options with proven efficacy were sparse. Dietary adjustments, nutritional support (per guidelines from the European Society for Clinical Nutrition and Metabolism for substantial weight loss or intractable vomiting), and opioid cessation were recommended by a consensus opinion. Antiemetic and prokinetic agents were also considered potentially beneficial. This consensus offers a global perspective on idiopathic gastroparesis.
UR - http://www.scopus.com/inward/record.url?scp=85211504715&partnerID=8YFLogxK
U2 - 10.1016/S2468-1253(24)00284-X
DO - 10.1016/S2468-1253(24)00284-X
M3 - Review article
AN - SCOPUS:85211504715
SN - 2468-1253
VL - 10
SP - 68
EP - 81
JO - The Lancet Gastroenterology and Hepatology
JF - The Lancet Gastroenterology and Hepatology
IS - 1
ER -