Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.

Ritesh Raju; Oleksandr Gromyko; Viktor Fedorenko; Jennifer Herrmann; Andriy Luzhetskyy; Rolf Müller

doi:10.1016/j.tetlet.2012.11.130

Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.

Ritesh Raju, Oleksandr Gromyko, Viktor Fedorenko, Jennifer Herrmann, Andriy Luzhetskyy, Rolf Müller

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Abstract

Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.

Original language	English
Pages (from-to)	900-902
Number of pages	3
Journal	Tetrahedron Letters
Volume	54
Issue number	8
DOIs	https://doi.org/10.1016/j.tetlet.2012.11.130
Publication status	Published - 2013

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10.1016/j.tetlet.2012.11.130

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title = "Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.",

abstract = "Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.",

author = "Ritesh Raju and Oleksandr Gromyko and Viktor Fedorenko and Jennifer Herrmann and Andriy Luzhetskyy and Rolf M{\"u}ller",

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T1 - Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.

AU - Raju, Ritesh

AU - Gromyko, Oleksandr

AU - Fedorenko, Viktor

AU - Herrmann, Jennifer

AU - Luzhetskyy, Andriy

AU - Müller, Rolf

PY - 2013

Y1 - 2013

N2 - Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.

AB - Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.

UR - http://handle.uws.edu.au:8081/1959.7/540644

U2 - 10.1016/j.tetlet.2012.11.130

DO - 10.1016/j.tetlet.2012.11.130

M3 - Article

SN - 0040-4039

VL - 54

SP - 900

EP - 902

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 8

ER -

Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.

Abstract

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