Saussureae Involucratae Herba (snow lotus) : review of chemical compositions and pharmacological properties

Guowei Gong, Jing Huang, Yang Yang, Baohui Qi, Guangyi Han, Yuzhong Zheng, Huan He, Kelvin Chan, Karl W. K. Tsim, Tina T. X. Dong

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Saussureae Involucratae Herba is the dried ground part of Saussurea involucrata (Kar. et Kir.) Sch.-Bip, which is also named as “Snow lotus” and being used in traditional Uyghur and/or Chinese medicine. This rare herb can be found at 4,000 m elevation in western part of Tianshan Mountain, Xinjiang China. According to China Pharmacopoeia (2015), the major pharmaceutical values of “Snow lotus” (Xuě liánhuā in Chinese) are alleviating rheumatoid arthritis, accelerating blood circulation and mitigating other “cold” syndromes. Traditionally, the clinical application of “Snow lotus” includes the treatments in inflammation-associated disorder, blood circulation acceleration and heat and dampness elimination. Recent studies suggested that “Snow lotus” possessed therapeutic effects associating with anti-cancer, anti-oxidation, adipogenesis suppression and neuroprotection activities, which were proposed to be related with its bioactive constitutes, i.e. acacetin, hispidulin, and rutin. In the present review, we aim to summarize pharmacological effects and underlying cell signaling pathways of “Snow lotus” in treating various medical problems.
Original languageEnglish
Article number1549
Number of pages11
JournalFrontiers in Pharmacology
Volume10
DOIs
Publication statusPublished - 2020

Open Access - Access Right Statement

© 2020 Gong, Huang, Yang, Qi, Han, Zheng, He, Chan, Tsim and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Keywords

  • alternative medicine
  • herbs
  • medicine_Chinese
  • therapeutic use

Fingerprint

Dive into the research topics of 'Saussureae Involucratae Herba (snow lotus) : review of chemical compositions and pharmacological properties'. Together they form a unique fingerprint.

Cite this