Selectivity in endocytosis of serum and cytosol proteins by macrophages in culture

R. T. Dean

doi:10.1016/0006-291X(78)91235-4

Selectivity in endocytosis of serum and cytosol proteins by macrophages in culture

R. T. Dean

MRC Clinical Research Centre

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

It was found that cultured mouse macrophages preferentially endocytose and degrade short half-life serum and cytosol proteins. With increasing duration of endocytosis, the components of longer half-life are increasingly endocytosed and degraded. The relevance of these observations to the selectivity of protein turnover is discussed.

Original language	English
Pages (from-to)	815-819
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	85
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(78)91235-4
Publication status	Published - 29 Nov 1978
Externally published	Yes

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title = "Selectivity in endocytosis of serum and cytosol proteins by macrophages in culture",

abstract = "It was found that cultured mouse macrophages preferentially endocytose and degrade short half-life serum and cytosol proteins. With increasing duration of endocytosis, the components of longer half-life are increasingly endocytosed and degraded. The relevance of these observations to the selectivity of protein turnover is discussed.",

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AB - It was found that cultured mouse macrophages preferentially endocytose and degrade short half-life serum and cytosol proteins. With increasing duration of endocytosis, the components of longer half-life are increasingly endocytosed and degraded. The relevance of these observations to the selectivity of protein turnover is discussed.

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Selectivity in endocytosis of serum and cytosol proteins by macrophages in culture

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