TY - JOUR
T1 - Serum C1q and tumor necrosis factor (TNF)-related protein 9 in women with Polycystic Ovary Syndrome
AU - Forouhi, Neda
AU - Saedisomeolia, Ahmad
AU - Djalali, Mahmoud
AU - Eshraghian, Mohammad Reza
AU - Morshedzadeh, Nava
AU - Zabetian-Targhi, Fateme
AU - Mahmoudi, Maryam
PY - 2016
Y1 - 2016
N2 - Aims. To compare CTRP9 levels in women with Polycystic Ovary Syndrome (PCOS) and without PCOS. Furthermore, to determine the correlation between serum CTRP9 levels and some variety of anthropometric and biochemical parameters. Methods. The study included 29 PCOS patients and 27 healthy volunteers of the same age and BMI. Body weight, height and waist circumference were assessed. Blood samples were taken for assessment of serum CTRP9 by enzyme-linked immunosorbent assay (ELISA) technique. In addition, blood samples were collected for fasting insulin, glucose, and lipid profiles, and homeostasis model of assessment-insulin resistance (HOMA-IR) values were calculated. Results. Similar serum CTRP9 were found in PCOS subjects and controls (8.8 ± 19.9 vs 5.0 ± 7.6 ng/mL). Serum CTRP9 concentration positively correlated with serum LDL-C and total cholesterol in patient group. However, no correlation between CTRP9 and other biochemical and anthropometric variables was found. Conclusion. Serum CTRP9 logs of PCOS participants exhibit a positive association with unfavorable lipid profile in this report.
AB - Aims. To compare CTRP9 levels in women with Polycystic Ovary Syndrome (PCOS) and without PCOS. Furthermore, to determine the correlation between serum CTRP9 levels and some variety of anthropometric and biochemical parameters. Methods. The study included 29 PCOS patients and 27 healthy volunteers of the same age and BMI. Body weight, height and waist circumference were assessed. Blood samples were taken for assessment of serum CTRP9 by enzyme-linked immunosorbent assay (ELISA) technique. In addition, blood samples were collected for fasting insulin, glucose, and lipid profiles, and homeostasis model of assessment-insulin resistance (HOMA-IR) values were calculated. Results. Similar serum CTRP9 were found in PCOS subjects and controls (8.8 ± 19.9 vs 5.0 ± 7.6 ng/mL). Serum CTRP9 concentration positively correlated with serum LDL-C and total cholesterol in patient group. However, no correlation between CTRP9 and other biochemical and anthropometric variables was found. Conclusion. Serum CTRP9 logs of PCOS participants exhibit a positive association with unfavorable lipid profile in this report.
KW - cytokines
KW - glycoproteins
KW - metabolic syndrome
KW - polycystic ovary syndrome
KW - tumor necrosis factor
UR - http://hdl.handle.net/1959.7/uws:34690
U2 - 10.1016/j.dsx.2016.03.012
DO - 10.1016/j.dsx.2016.03.012
M3 - Article
SN - 1871-4021
VL - 10
SP - S131-S134
JO - Diabetes and Metabolic Syndrome
JF - Diabetes and Metabolic Syndrome
IS - 2\, Suppl. 1
ER -