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Serum C1q and tumor necrosis factor (TNF)-related protein 9 in women with Polycystic Ovary Syndrome

  • Neda Forouhi
  • , Ahmad Saedisomeolia
  • , Mahmoud Djalali
  • , Mohammad Reza Eshraghian
  • , Nava Morshedzadeh
  • , Fateme Zabetian-Targhi
  • , Maryam Mahmoudi

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Aims. To compare CTRP9 levels in women with Polycystic Ovary Syndrome (PCOS) and without PCOS. Furthermore, to determine the correlation between serum CTRP9 levels and some variety of anthropometric and biochemical parameters. Methods. The study included 29 PCOS patients and 27 healthy volunteers of the same age and BMI. Body weight, height and waist circumference were assessed. Blood samples were taken for assessment of serum CTRP9 by enzyme-linked immunosorbent assay (ELISA) technique. In addition, blood samples were collected for fasting insulin, glucose, and lipid profiles, and homeostasis model of assessment-insulin resistance (HOMA-IR) values were calculated. Results. Similar serum CTRP9 were found in PCOS subjects and controls (8.8 ± 19.9 vs 5.0 ± 7.6 ng/mL). Serum CTRP9 concentration positively correlated with serum LDL-C and total cholesterol in patient group. However, no correlation between CTRP9 and other biochemical and anthropometric variables was found. Conclusion. Serum CTRP9 logs of PCOS participants exhibit a positive association with unfavorable lipid profile in this report.
Original languageEnglish
Pages (from-to)S131-S134
Number of pages4
JournalDiabetes and Metabolic Syndrome
Volume10
Issue number2\, Suppl. 1
DOIs
Publication statusPublished - 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • cytokines
  • glycoproteins
  • metabolic syndrome
  • polycystic ovary syndrome
  • tumor necrosis factor

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