SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study

Daniel E. Adkins, Amit N. Khachane, Joseph L. McClay, Karolina Åberg, Jozsef Bukszár, Patrick F. Sullivan, Edwin J. C. G. Van den Oord

    Research output: Contribution to journalArticlepeer-review

    40 Citations (SciVal)

    Abstract

    Identifying specific neuroactive pathways involved in antipsychotic pharmacology is vital to developing improved therapeutic strategies for schizophrenia. Our results implicate the PGE2 pathway as a novel biomarker mediating response to three atypical antipsychotic drugs.
    Original languageEnglish
    Pages (from-to)200-201
    Number of pages2
    JournalSchizophrenia Research
    Volume135
    Issue number45352
    DOIs
    Publication statusPublished - 2012

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