SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study

Daniel E. Adkins; Amit N. Khachane; Joseph L. McClay; Karolina Åberg; Jozsef Bukszár; Patrick F. Sullivan; Edwin J. C. G. Van den Oord

doi:10.1016/j.schres.2011.11.002

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study

Daniel E. Adkins
, Amit N. Khachane
, Joseph L. McClay
, Karolina Åberg
, Jozsef Bukszár
, Patrick F. Sullivan
, Edwin J. C. G. Van den Oord

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Identifying specific neuroactive pathways involved in antipsychotic pharmacology is vital to developing improved therapeutic strategies for schizophrenia. Our results implicate the PGE2 pathway as a novel biomarker mediating response to three atypical antipsychotic drugs.

Original language	English
Pages (from-to)	200-201
Number of pages	2
Journal	Schizophrenia Research
Volume	135
Issue number	45352
DOIs	https://doi.org/10.1016/j.schres.2011.11.002
Publication status	Published - 2012

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10.1016/j.schres.2011.11.002

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Adkins, D. E., Khachane, A. N., McClay, J. L., Åberg, K., Bukszár, J., Sullivan, P. F., & Van den Oord, E. J. C. G. (2012). SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study. Schizophrenia Research, 135(45352), 200-201. https://doi.org/10.1016/j.schres.2011.11.002

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title = "SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study",

abstract = "Identifying specific neuroactive pathways involved in antipsychotic pharmacology is vital to developing improved therapeutic strategies for schizophrenia. Our results implicate the PGE2 pathway as a novel biomarker mediating response to three atypical antipsychotic drugs.",

author = "Adkins, \{Daniel E.\} and Khachane, \{Amit N.\} and McClay, \{Joseph L.\} and Karolina {\AA}berg and Jozsef Buksz{\'a}r and Sullivan, \{Patrick F.\} and \{Van den Oord\}, \{Edwin J. C. G.\}",

year = "2012",

doi = "10.1016/j.schres.2011.11.002",

language = "English",

volume = "135",

pages = "200--201",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier B.V.",

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Adkins, DE, Khachane, AN, McClay, JL, Åberg, K, Bukszár, J, Sullivan, PF & Van den Oord, EJCG 2012, 'SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study', Schizophrenia Research, vol. 135, no. 45352, pp. 200-201. https://doi.org/10.1016/j.schres.2011.11.002

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study. / Adkins, Daniel E.; Khachane, Amit N.; McClay, Joseph L. et al.
In: Schizophrenia Research, Vol. 135, No. 45352, 2012, p. 200-201.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study

AU - Adkins, Daniel E.

AU - Khachane, Amit N.

AU - McClay, Joseph L.

AU - Åberg, Karolina

AU - Bukszár, Jozsef

AU - Sullivan, Patrick F.

AU - Van den Oord, Edwin J. C. G.

PY - 2012

Y1 - 2012

N2 - Identifying specific neuroactive pathways involved in antipsychotic pharmacology is vital to developing improved therapeutic strategies for schizophrenia. Our results implicate the PGE2 pathway as a novel biomarker mediating response to three atypical antipsychotic drugs.

AB - Identifying specific neuroactive pathways involved in antipsychotic pharmacology is vital to developing improved therapeutic strategies for schizophrenia. Our results implicate the PGE2 pathway as a novel biomarker mediating response to three atypical antipsychotic drugs.

UR - http://handle.uws.edu.au:8081/1959.7/531798

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DO - 10.1016/j.schres.2011.11.002

M3 - Article

SN - 0920-9964

VL - 135

SP - 200

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JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 45352

ER -

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response : data from the CATIE study

Abstract

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