TY - JOUR
T1 - Spirostanol saponins from the fibrous roots of Ophiopogon japonicus (Thunb.) Ker-Gawl
AU - Duan, Chang-Ling
AU - Li, Yu-Juan
AU - Li, Peng
AU - Jiang, Yong
AU - Liu, Jian-Xun
AU - Tu, Peng-Fei
PY - 2010
Y1 - 2010
N2 - Three new steroidal saponins, (25R)-ruscogenin-3-yl a-l-rhamnopyranosyl- (1→2)-[β-D-xylopyranosyl-( 1→4)]-β-D-glucopyranoside (1), diosgenin-3-yl 2-O-acetyl-a-l-rhamnopyranosyl-(1→2)-[β-D- xylopyranosyl-( 1→4)]-β-D-glucopyranoside (2), and pennogenin-3-yl 2-O-acetyl-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl- (1→4)]-β-D-glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (THUNB.) KER-GAWL. Their structures were determined by spectroscopic methods including IR, HR-ESI-MS, and 1D- and 2D-NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines.
AB - Three new steroidal saponins, (25R)-ruscogenin-3-yl a-l-rhamnopyranosyl- (1→2)-[β-D-xylopyranosyl-( 1→4)]-β-D-glucopyranoside (1), diosgenin-3-yl 2-O-acetyl-a-l-rhamnopyranosyl-(1→2)-[β-D- xylopyranosyl-( 1→4)]-β-D-glucopyranoside (2), and pennogenin-3-yl 2-O-acetyl-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl- (1→4)]-β-D-glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (THUNB.) KER-GAWL. Their structures were determined by spectroscopic methods including IR, HR-ESI-MS, and 1D- and 2D-NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines.
UR - http://handle.uws.edu.au:8081/1959.7/546765
U2 - 10.1002/hlca.200900165
DO - 10.1002/hlca.200900165
M3 - Article
SN - 0018-019X
VL - 93
SP - 227
EP - 232
JO - Helvetica Chimica Acta
JF - Helvetica Chimica Acta
IS - 2
ER -