TY - JOUR
T1 - St. John's Wort for the treatment of psychiatric disorders
AU - Sarris, Jerome
PY - 2013
Y1 - 2013
N2 - St. John's wort (Hypericum perforatum) has been extensively studied and reviewed for its use in depression; however, there is less salient discussion on its clinical application for a range of other psychiatric disorders. This article outlines the current evidence of the efficacy of St John's wort in common psychiatric disorders, including major depression, bipolar depression, attention-deficit hyperactivity disorder, obsessive-compulsive disorder, social phobia, and somatization disorder. Mechanisms of action, including emerging pharmacogenetic data, safety, and clinical considerations are also detailed.
AB - St. John's wort (Hypericum perforatum) has been extensively studied and reviewed for its use in depression; however, there is less salient discussion on its clinical application for a range of other psychiatric disorders. This article outlines the current evidence of the efficacy of St John's wort in common psychiatric disorders, including major depression, bipolar depression, attention-deficit hyperactivity disorder, obsessive-compulsive disorder, social phobia, and somatization disorder. Mechanisms of action, including emerging pharmacogenetic data, safety, and clinical considerations are also detailed.
KW - Hypericum perforatum
KW - St John's wort
KW - alternative medicine
KW - antidepressants
KW - anxiety
KW - depression_mental
UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:39706
UR - https://www.clinicalkey.com.au/#!/content/journal/1-s2.0-S0193953X13000051
U2 - 10.1016/j.psc.2013.01.004
DO - 10.1016/j.psc.2013.01.004
M3 - Article
SN - 1558-3147
SN - 0193-953X
VL - 36
SP - 65
EP - 72
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 1
ER -