TY - JOUR
T1 - Studies of a mouse model of cardic c a1A-adrenergic receptor over expression provide evidence for a critical role of RhoA/ROCK signalling in cardiac contractility
AU - Yu, Z.
AU - Tan, J.
AU - McMahon, A.
AU - Iismaa, S.
AU - Xiao, X.
AU - Kesteven, S.
AU - Reichelt, M
AU - Mohl, M.
AU - Dai, Y.
AU - Sketchley, A.
AU - Yang, L.
AU - Gong, H.
AU - Fatkin, D.
AU - Allen, D.
AU - Head, S.
AU - Graham, R.
AU - Feneley, M.
PY - 2013
Y1 - 2013
N2 - Despite evidence implicating the _1A-adrenergic receptor (AR) in the development of cardiac hypertrophy, we have previously reported that transgenic (TG) mice with cardiac-restricted _1A-AR overexpression (170-fold) exhibit enhanced ventricular contractility but not hypertrophy in vivo.
AB - Despite evidence implicating the _1A-adrenergic receptor (AR) in the development of cardiac hypertrophy, we have previously reported that transgenic (TG) mice with cardiac-restricted _1A-AR overexpression (170-fold) exhibit enhanced ventricular contractility but not hypertrophy in vivo.
UR - http://hdl.handle.net/1959.7/uws:42205
U2 - 10.1016/j.hlc.2013.05.143
DO - 10.1016/j.hlc.2013.05.143
M3 - Article
SN - 1443-9506
VL - 22
SP - S59-S59
JO - Heart , Lung and Circulation
JF - Heart , Lung and Circulation
IS - Supplement 1
ER -