The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes

Motahareh Makhdoomi Arzati; Niyaz Mohammadzadeh Honarvar; Ahmad Saedisomeolia; Siyamand Anvari; Mohammad Effatpanah; Raoofe Makhdoomi Arzati; Mir Saeed Yekaninejad; Rezvan Hashemi; Mahmoud Djalali

doi:10.5812/ijem.57927

The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes

Motahareh Makhdoomi Arzati, Niyaz Mohammadzadeh Honarvar, Ahmad Saedisomeolia, Siyamand Anvari, Mohammad Effatpanah, Raoofe Makhdoomi Arzati, Mir Saeed Yekaninejad, Rezvan Hashemi, Mahmoud Djalali

Western Sydney University

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Background: Lipid and glycemic abnormalities are prevalent in diabetes leading to long term complications. Use of safe and natural foods instead of medications is now considered by many scientists. Objectives: This study aimed at determining the effect of ginger on lipid and glucose levels of patients with type 2 diabetes mellitus. Methods: In a double-blind placebo-controlled trial, 50 patients with type 2 diabetes were randomly allocated to 2 groups of intervention (n = 25) and placebo (n = 25). Each patient received 2000 mg per day of ginger supplements or placebo for 10 weeks. Serum levels of fasting blood sugar (FBS), total cholesterol (TC), triacylglycerol (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and glycosylated hemoglobin (HbA1C) were analyzed. Daily dietary intakes and anthropometric parameters were also determined. Results: Data from 45 patients were analyzed (23 patients in the ginger group and 22 patients in the control group) at the end of the study. Ginger consumption significantly reduced serum levels of fasting blood glucose (-26.30 ± 35.27 vs. 11.91 ± 38.58 mg/dl; P = 0.001) and hemoglobin A1C (-0.38 ± 0.35 vs. 0.22 ± 0.29 %; P < 0.0001) compared to the placebo group. Ginger consumption also reduced the ratio of LDL-C/HDL-C (2.64 ± 0.85 vs. 2.35 ± 0.8; P = 0.009). However, there was no significant change in serum concentrations of triglycerides, total cholesterol, LDL-C, and HDL-C due to the ginger supplements. Conclusions: The current results showed that ginger could reduce serum levels of fasting blood glucose and hemoglobin A1C in patients with diabetes.

Original language	English
Article number	e57927
Number of pages	7
Journal	International Journal of Endocrinology and Metabolism
Volume	15
Issue number	4
DOIs	https://doi.org/10.5812/ijem.57927
Publication status	Published - 2017

Open Access - Access Right Statement

© 2017, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Keywords

blood sugar
diabetes
ginger
glycosylated hemoglobin
lipids
non, insulin, dependent diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5812/ijem.57927

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Makhdoomi Arzati, M., Mohammadzadeh Honarvar, N., Saedisomeolia, A., Anvari, S., Effatpanah, M., Makhdoomi Arzati, R., Yekaninejad, M. S., Hashemi, R., & Djalali, M. (2017). The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes. International Journal of Endocrinology and Metabolism, 15(4), Article e57927. https://doi.org/10.5812/ijem.57927

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title = "The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes",

abstract = "Background: Lipid and glycemic abnormalities are prevalent in diabetes leading to long term complications. Use of safe and natural foods instead of medications is now considered by many scientists. Objectives: This study aimed at determining the effect of ginger on lipid and glucose levels of patients with type 2 diabetes mellitus. Methods: In a double-blind placebo-controlled trial, 50 patients with type 2 diabetes were randomly allocated to 2 groups of intervention (n = 25) and placebo (n = 25). Each patient received 2000 mg per day of ginger supplements or placebo for 10 weeks. Serum levels of fasting blood sugar (FBS), total cholesterol (TC), triacylglycerol (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and glycosylated hemoglobin (HbA1C) were analyzed. Daily dietary intakes and anthropometric parameters were also determined. Results: Data from 45 patients were analyzed (23 patients in the ginger group and 22 patients in the control group) at the end of the study. Ginger consumption significantly reduced serum levels of fasting blood glucose (-26.30 ± 35.27 vs. 11.91 ± 38.58 mg/dl; P = 0.001) and hemoglobin A1C (-0.38 ± 0.35 vs. 0.22 ± 0.29 %; P < 0.0001) compared to the placebo group. Ginger consumption also reduced the ratio of LDL-C/HDL-C (2.64 ± 0.85 vs. 2.35 ± 0.8; P = 0.009). However, there was no significant change in serum concentrations of triglycerides, total cholesterol, LDL-C, and HDL-C due to the ginger supplements. Conclusions: The current results showed that ginger could reduce serum levels of fasting blood glucose and hemoglobin A1C in patients with diabetes.",

keywords = "blood sugar, diabetes, ginger, glycosylated hemoglobin, lipids, non, insulin, dependent diabetes",

author = "{Makhdoomi Arzati}, Motahareh and {Mohammadzadeh Honarvar}, Niyaz and Ahmad Saedisomeolia and Siyamand Anvari and Mohammad Effatpanah and {Makhdoomi Arzati}, Raoofe and Yekaninejad, {Mir Saeed} and Rezvan Hashemi and Mahmoud Djalali",

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Makhdoomi Arzati, M, Mohammadzadeh Honarvar, N, Saedisomeolia, A, Anvari, S, Effatpanah, M, Makhdoomi Arzati, R, Yekaninejad, MS, Hashemi, R & Djalali, M 2017, 'The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes', International Journal of Endocrinology and Metabolism, vol. 15, no. 4, e57927. https://doi.org/10.5812/ijem.57927

TY - JOUR

T1 - The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes

AU - Makhdoomi Arzati, Motahareh

AU - Mohammadzadeh Honarvar, Niyaz

AU - Saedisomeolia, Ahmad

AU - Anvari, Siyamand

AU - Effatpanah, Mohammad

AU - Makhdoomi Arzati, Raoofe

AU - Yekaninejad, Mir Saeed

AU - Hashemi, Rezvan

AU - Djalali, Mahmoud

PY - 2017

Y1 - 2017

N2 - Background: Lipid and glycemic abnormalities are prevalent in diabetes leading to long term complications. Use of safe and natural foods instead of medications is now considered by many scientists. Objectives: This study aimed at determining the effect of ginger on lipid and glucose levels of patients with type 2 diabetes mellitus. Methods: In a double-blind placebo-controlled trial, 50 patients with type 2 diabetes were randomly allocated to 2 groups of intervention (n = 25) and placebo (n = 25). Each patient received 2000 mg per day of ginger supplements or placebo for 10 weeks. Serum levels of fasting blood sugar (FBS), total cholesterol (TC), triacylglycerol (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and glycosylated hemoglobin (HbA1C) were analyzed. Daily dietary intakes and anthropometric parameters were also determined. Results: Data from 45 patients were analyzed (23 patients in the ginger group and 22 patients in the control group) at the end of the study. Ginger consumption significantly reduced serum levels of fasting blood glucose (-26.30 ± 35.27 vs. 11.91 ± 38.58 mg/dl; P = 0.001) and hemoglobin A1C (-0.38 ± 0.35 vs. 0.22 ± 0.29 %; P < 0.0001) compared to the placebo group. Ginger consumption also reduced the ratio of LDL-C/HDL-C (2.64 ± 0.85 vs. 2.35 ± 0.8; P = 0.009). However, there was no significant change in serum concentrations of triglycerides, total cholesterol, LDL-C, and HDL-C due to the ginger supplements. Conclusions: The current results showed that ginger could reduce serum levels of fasting blood glucose and hemoglobin A1C in patients with diabetes.

AB - Background: Lipid and glycemic abnormalities are prevalent in diabetes leading to long term complications. Use of safe and natural foods instead of medications is now considered by many scientists. Objectives: This study aimed at determining the effect of ginger on lipid and glucose levels of patients with type 2 diabetes mellitus. Methods: In a double-blind placebo-controlled trial, 50 patients with type 2 diabetes were randomly allocated to 2 groups of intervention (n = 25) and placebo (n = 25). Each patient received 2000 mg per day of ginger supplements or placebo for 10 weeks. Serum levels of fasting blood sugar (FBS), total cholesterol (TC), triacylglycerol (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and glycosylated hemoglobin (HbA1C) were analyzed. Daily dietary intakes and anthropometric parameters were also determined. Results: Data from 45 patients were analyzed (23 patients in the ginger group and 22 patients in the control group) at the end of the study. Ginger consumption significantly reduced serum levels of fasting blood glucose (-26.30 ± 35.27 vs. 11.91 ± 38.58 mg/dl; P = 0.001) and hemoglobin A1C (-0.38 ± 0.35 vs. 0.22 ± 0.29 %; P < 0.0001) compared to the placebo group. Ginger consumption also reduced the ratio of LDL-C/HDL-C (2.64 ± 0.85 vs. 2.35 ± 0.8; P = 0.009). However, there was no significant change in serum concentrations of triglycerides, total cholesterol, LDL-C, and HDL-C due to the ginger supplements. Conclusions: The current results showed that ginger could reduce serum levels of fasting blood glucose and hemoglobin A1C in patients with diabetes.

KW - blood sugar

KW - diabetes

KW - ginger

KW - glycosylated hemoglobin

KW - lipids

KW - non, insulin, dependent diabetes

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:43121

U2 - 10.5812/ijem.57927

DO - 10.5812/ijem.57927

M3 - Article

SN - 1726-913X

VL - 15

JO - International Journal of Endocrinology and Metabolism

JF - International Journal of Endocrinology and Metabolism

IS - 4

M1 - e57927

ER -

The effects of ginger on fasting blood sugar, hemoglobin A1c, and lipid profiles in patients with type 2 diabetes

Abstract

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Keywords

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