TY - JOUR
T1 - The effects of lifestyle and/or vitamin D supplementation interventions on pregnancy outcomes
T2 - what have we learned from the DALI studies?
AU - Harreiter, Jurgen
AU - Desoye, Gernot
AU - Poppel, Mireille N. M. van
AU - Kautzky-Willer, Alexandra
AU - Dunne, Fidelma
AU - Corcoy, Rosa
AU - Devlieger, Roland
AU - DALI Consortium,
AU - Simmons, David
AU - Adelantado, Juan M.
AU - Damm, Peter
AU - Mathiesen, Elizabeth Reinhardt
AU - Jensen, Dorte Moeller
AU - Anderson, Lise Lotte T.
AU - Lapolla, Annunziata
AU - Dalfra, Maria G.
AU - Bertolotto, Alessandra
AU - Wender-Ozegowska, Ewa
AU - Zawiejska, Agnieszka
AU - Hill, David J.
AU - Snoek, Frank J.
PY - 2019
Y1 - 2019
N2 - Purpose of Review: The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI"‰â‰¥"‰29 kg/m2. Recent Findings: Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Summary: Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.Correction: The original version of this review article unfortunately contained a mistake. The ISRCTN number reflected in "DALI Study Design" and "Compliance with Ethical Standards" sections was incorrect. It should be "ISRCTN70595832" instead of "ISRCTN7059583". There is an Author Correction to the Article - https://doi.org/10.1007/s11892-020-01322-y
AB - Purpose of Review: The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI"‰â‰¥"‰29 kg/m2. Recent Findings: Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Summary: Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.Correction: The original version of this review article unfortunately contained a mistake. The ISRCTN number reflected in "DALI Study Design" and "Compliance with Ethical Standards" sections was incorrect. It should be "ISRCTN70595832" instead of "ISRCTN7059583". There is an Author Correction to the Article - https://doi.org/10.1007/s11892-020-01322-y
KW - diabetes in pregnancy
KW - health aspects
KW - lifestyles
KW - obesity
KW - vitamin D
UR - http://hdl.handle.net/1959.7/uws:54013
UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/10.1007/s11892-019-1282-7
U2 - 10.1007/s11892-019-1282-7
DO - 10.1007/s11892-019-1282-7
M3 - Article
SN - 1534-4827
VL - 19
JO - Current Diabetes Reports
JF - Current Diabetes Reports
IS - 12
M1 - 162
ER -
