The genetics and genomics of cyanobacterial toxicity

Brett A. Neilan; Leanne A. Pearson; Michelle C. Moffitt; Troco Kaan Mihali; M. Kaebernick; Ralf Kellmann; Francesco Pomati; H. Kenneth Hudnell

The genetics and genomics of cyanobacterial toxicity

Brett A. Neilan, Leanne A. Pearson, Michelle C. Moffitt, Troco Kaan Mihali, M. Kaebernick, Ralf Kellmann, Francesco Pomati, H. Kenneth Hudnell

Research output: Chapter in Book / Conference Paper › Chapter

30 Citations (Scopus)

Abstract

![CDATA[The past ten years has witnessed major advances in our understanding of natural product biosynthesis, including the genetic basis for toxin production by a number of groups of cyanobacteria. Cyanobacteria produce an unparalleled array of bioactive secondary metabolites; including alkaloids, polyketides and non–ribosomal peptides, some of which are potent toxins. This paper addresses the molecular genetics underlying cyanotoxin production in fresh and brackish water environments. The major toxins that have been investigated include microcystin, cylindrospermopsin, nodularin, the paralytic shellfish poisons (PSP), including saxitoxin, and the anatoxins.]]

Original language	English
Title of host publication	Cyanobacterial Harmful Algal Blooms : State of the Science and Research Needs
Place of Publication	U.S.A
Publisher	Springer
Pages	417-452
Number of pages	36
ISBN (Print)	9780387758640
Publication status	Published - 2008

Keywords

biosynthesis
molecular genetics
toxins
cyanobacterial toxins
cyanobacteria

Cite this

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title = "The genetics and genomics of cyanobacterial toxicity",

abstract = "![CDATA[The past ten years has witnessed major advances in our understanding of natural product biosynthesis, including the genetic basis for toxin production by a number of groups of cyanobacteria. Cyanobacteria produce an unparalleled array of bioactive secondary metabolites; including alkaloids, polyketides and non–ribosomal peptides, some of which are potent toxins. This paper addresses the molecular genetics underlying cyanotoxin production in fresh and brackish water environments. The major toxins that have been investigated include microcystin, cylindrospermopsin, nodularin, the paralytic shellfish poisons (PSP), including saxitoxin, and the anatoxins.]]",

keywords = "biosynthesis, molecular genetics, toxins, cyanobacterial toxins, cyanobacteria",

author = "Neilan, {Brett A.} and Pearson, {Leanne A.} and Moffitt, {Michelle C.} and Mihali, {Troco Kaan} and M. Kaebernick and Ralf Kellmann and Francesco Pomati and Hudnell, {H. Kenneth}",

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TY - CHAP

T1 - The genetics and genomics of cyanobacterial toxicity

AU - Neilan, Brett A.

AU - Pearson, Leanne A.

AU - Moffitt, Michelle C.

AU - Mihali, Troco Kaan

AU - Kaebernick, M.

AU - Kellmann, Ralf

AU - Pomati, Francesco

AU - Hudnell, H. Kenneth

PY - 2008

Y1 - 2008

N2 - ![CDATA[The past ten years has witnessed major advances in our understanding of natural product biosynthesis, including the genetic basis for toxin production by a number of groups of cyanobacteria. Cyanobacteria produce an unparalleled array of bioactive secondary metabolites; including alkaloids, polyketides and non–ribosomal peptides, some of which are potent toxins. This paper addresses the molecular genetics underlying cyanotoxin production in fresh and brackish water environments. The major toxins that have been investigated include microcystin, cylindrospermopsin, nodularin, the paralytic shellfish poisons (PSP), including saxitoxin, and the anatoxins.]]

AB - ![CDATA[The past ten years has witnessed major advances in our understanding of natural product biosynthesis, including the genetic basis for toxin production by a number of groups of cyanobacteria. Cyanobacteria produce an unparalleled array of bioactive secondary metabolites; including alkaloids, polyketides and non–ribosomal peptides, some of which are potent toxins. This paper addresses the molecular genetics underlying cyanotoxin production in fresh and brackish water environments. The major toxins that have been investigated include microcystin, cylindrospermopsin, nodularin, the paralytic shellfish poisons (PSP), including saxitoxin, and the anatoxins.]]

KW - biosynthesis

KW - molecular genetics

KW - toxins

KW - cyanobacterial toxins

KW - cyanobacteria

UR - http://handle.uws.edu.au:8081/1959.7/488915

M3 - Chapter

SN - 9780387758640

SP - 417

EP - 452

BT - Cyanobacterial Harmful Algal Blooms : State of the Science and Research Needs

PB - Springer

CY - U.S.A

ER -

The genetics and genomics of cyanobacterial toxicity

Abstract

Keywords

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