The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017

Arash Etemadi; Saeid Safiri; Sadaf G. Sepanlou; Kevin Ikuta; Catherine Bisignano; Ramin Shakeri; Mohammad Amani; Christina Fitzmaurice; Molly R. Nixon; Nooshin Abbasi; Hassan Abolhassani; Shailesh M. Advani; Mohsen Afarideh; Tomi Akinyemiju; Tahiya Alam; Mahtab Alikhani; Vahid Alipour; Christine A. Allen; Amir Almasi-Hashiani; Jalal Arabloo; Reza Assadi; Suleman Atique; Ashish Awasthi; Ahad Bakhtiari; Masoud Behzadifar; Kidanemaryam Berhe; Neeraj Bhala; Ali Bijani; Muhammad Shahdaat Bin Sayeed; Tone Bjørge; Antonio M. Borzì; Dejana Braithwaite; Hermann Brenner; Giulia Carreras; Felix Carvalho; Carlos A. Castañeda-Orjuela; Franz Castro; Dinh-Toi Chu; Vera M. Costa; Ahmad Daryani; Dragos Virgil Davitoiu; Gebre T. Demoz; Asmamaw Bizuneh Demis; Edgar Denova-Gutiérrez; Subhojit Dey; Mostafa Dianati Nasab; Shirin Djalalinia; Mohammad Hassan Emamian; Mohammad Farahmand; Joāo C. Fernandes; Florian Fischer; Masoud Foroutan; Mohamed M. Gad; Silvano Gallus; Gebreamlak Gebremedhn Gebremeskel; Getnet Azeze Gedefew; Fatemeh Ghaseni-Kebria; Giuseppe Gorini; Nima Hafezi-Nejad; Arvin Haj-Mirzaian; Josep M. Haro; James D. Harvey; Amir Hasanzadeh; Maryam Hashemian; Hamid Y. Hassen; Simon I. Hay; Hagos D. Hidru; Mihaela Hostiuc; Mowafa Househ; Olayinka Stephen Ilesanmi; Milena D. Ilic; Kaire Innos; Farhad Islami; Spencer L. James; Ensiyeh Jenabi; Rohollah Kalhor; Farin Kamangar; Amir Kasaeian; Andre Pascal Kengne; Yousef Saleh Khader; Rovshan Khalilov; Ejaz Ahmad Khan; Gulfaraz Khan; Maryam Khayamzadeh; Maryam Khazaee-Pool; Salman Khazaei; Abdullah T. Khoja; Fatemah Khosravi Shadmani; Yun Jin Kim; Jonathan M. Kocarnik; Hamidreza Komaki; Ai Koyanagi; Vivek Kumar; Carlo La Vecchia; Alan D. Lopez; Raimundas Lunevicius; Navid Manafi; Ana-Laura Manda; Birhanu Geta; Hailemariam Meheretu; Getnet Mengistu; Bartosz Miazgowski; Sayed Mostafa Mir; Karzan Abdulmuhsin Mohammad; Naser Mohammad Gholi Mezerji; Mahdi Mohammadian; Abdollah Mohammadian-Hafshejani; Reza Mohammadpourhodki; Shafiu Mohammed; Farnam Mohebi; Ali H. Mokdad; Lorenzo Monasta; Mahmood Moosazadeh; Maryam Moossavi; Ghobad Moradi; Farhad Moradpour; Rahmatollah Moradzadeh; Ilais Moreno Velasquez; Abbas Mosapour; Mehdi Naderi; Gurudatta Naik; Farid Najafi; Azin Nahvijou; Ionut Negoi; Rajan Nikbakhsh; Marzieh Nojomi; Andrew T. Olagunju; Tinuke O. Olagunju; Eyal Oren; Hadi Parsian; Cristiano Piccinelli; Akram Pourshams; Hossein Poustchi; Navid Rabiee; Amir Radfar; Alireza Rafiei; Mahdi Rahimi; Marveh Rahmati; A. M. N. Renzaho; null et al

doi:10.1016/S2468-1253(19)30328-0

The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017

Arash Etemadi, Saeid Safiri, Sadaf G. Sepanlou, Kevin Ikuta, Catherine Bisignano, Ramin Shakeri, Mohammad Amani, Christina Fitzmaurice, Molly R. Nixon, Nooshin Abbasi, Hassan Abolhassani, Shailesh M. Advani, Mohsen Afarideh, Tomi Akinyemiju, Tahiya Alam, Mahtab Alikhani, Vahid Alipour, Christine A. Allen, Amir Almasi-Hashiani, Jalal ArablooReza Assadi, Suleman Atique, Ashish Awasthi, Ahad Bakhtiari, Masoud Behzadifar, Kidanemaryam Berhe, Neeraj Bhala, Ali Bijani, Muhammad Shahdaat Bin Sayeed, Tone Bjørge, Antonio M. Borzì, Dejana Braithwaite, Hermann Brenner, Giulia Carreras, Felix Carvalho, Carlos A. Castañeda-Orjuela, Franz Castro, Dinh-Toi Chu, Vera M. Costa, Ahmad Daryani, Dragos Virgil Davitoiu, Gebre T. Demoz, Asmamaw Bizuneh Demis, Edgar Denova-Gutiérrez, Subhojit Dey, Mostafa Dianati Nasab, Shirin Djalalinia, Mohammad Hassan Emamian, Mohammad Farahmand, Joāo C. Fernandes, Florian Fischer, Masoud Foroutan, Mohamed M. Gad, Silvano Gallus, Gebreamlak Gebremedhn Gebremeskel, Getnet Azeze Gedefew, Fatemeh Ghaseni-Kebria, Giuseppe Gorini, Nima Hafezi-Nejad, Arvin Haj-Mirzaian, Josep M. Haro, James D. Harvey, Amir Hasanzadeh, Maryam Hashemian, Hamid Y. Hassen, Simon I. Hay, Hagos D. Hidru, Mihaela Hostiuc, Mowafa Househ, Olayinka Stephen Ilesanmi, Milena D. Ilic, Kaire Innos, Farhad Islami, Spencer L. James, Ensiyeh Jenabi, Rohollah Kalhor, Farin Kamangar, Amir Kasaeian, Andre Pascal Kengne, Yousef Saleh Khader, Rovshan Khalilov, Ejaz Ahmad Khan, Gulfaraz Khan, Maryam Khayamzadeh, Maryam Khazaee-Pool, Salman Khazaei, Abdullah T. Khoja, Fatemah Khosravi Shadmani, Yun Jin Kim, Jonathan M. Kocarnik, Hamidreza Komaki, Ai Koyanagi, Vivek Kumar, Carlo La Vecchia, Alan D. Lopez, Raimundas Lunevicius, Navid Manafi, Ana-Laura Manda, Birhanu Geta, Hailemariam Meheretu, Getnet Mengistu, Bartosz Miazgowski, Sayed Mostafa Mir, Karzan Abdulmuhsin Mohammad, Naser Mohammad Gholi Mezerji, Mahdi Mohammadian, Abdollah Mohammadian-Hafshejani, Reza Mohammadpourhodki, Shafiu Mohammed, Farnam Mohebi, Ali H. Mokdad, Lorenzo Monasta, Mahmood Moosazadeh, Maryam Moossavi, Ghobad Moradi, Farhad Moradpour, Rahmatollah Moradzadeh, Ilais Moreno Velasquez, Abbas Mosapour, Mehdi Naderi, Gurudatta Naik, Farid Najafi, Azin Nahvijou, Ionut Negoi, Rajan Nikbakhsh, Marzieh Nojomi, Andrew T. Olagunju, Tinuke O. Olagunju, Eyal Oren, Hadi Parsian, Cristiano Piccinelli, Akram Pourshams, Hossein Poustchi, Navid Rabiee, Amir Radfar, Alireza Rafiei, Mahdi Rahimi, Marveh Rahmati, A. M. N. Renzaho, et al

Western Sydney University

Research output: Contribution to journal › Article › peer-review

462 Citations (Scopus)

Abstract

Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1Â·22 million (95% UI 1Â·19–1Â·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19Â·1 million (18Â·7–19Â·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29Â·5, 28Â·2–31Â·0 per 100 000 population) and east Asia (28Â·6, 27Â·3–30Â·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38Â·2% (21Â·1–57Â·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24Â·5% (20Â·0–28Â·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation.

Original language	English
Pages (from-to)	42-54
Number of pages	13
Journal	The Lancet Gastroenterology and Hepatology
Volume	5
Issue number	1
DOIs	https://doi.org/10.1016/S2468-1253(19)30328-0
Publication status	Published - 2020

Open Access - Access Right Statement

Keywords

cancer
disabilities
mortility
stomach

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S2468-1253(19)30328-0

Cite this

Etemadi, A., Safiri, S., Sepanlou, S. G., Ikuta, K., Bisignano, C., Shakeri, R., Amani, M., Fitzmaurice, C., Nixon, M. R., Abbasi, N., Abolhassani, H., Advani, S. M., Afarideh, M., Akinyemiju, T., Alam, T., Alikhani, M., Alipour, V., Allen, C. A., Almasi-Hashiani, A., ... et al (2020). The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017. The Lancet Gastroenterology and Hepatology, 5(1), 42-54. https://doi.org/10.1016/S2468-1253(19)30328-0

@article{1b4359f229884454b734d096e3285554,

title = "The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017",

abstract = "Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1{\^A}·22 million (95% UI 1{\^A}·19–1{\^A}·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19{\^A}·1 million (18{\^A}·7–19{\^A}·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29{\^A}·5, 28{\^A}·2–31{\^A}·0 per 100 000 population) and east Asia (28{\^A}·6, 27{\^A}·3–30{\^A}·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38{\^A}·2% (21{\^A}·1–57{\^A}·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24{\^A}·5% (20{\^A}·0–28{\^A}·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation.",

keywords = "cancer, disabilities, mortility, stomach",

author = "Arash Etemadi and Saeid Safiri and Sepanlou, {Sadaf G.} and Kevin Ikuta and Catherine Bisignano and Ramin Shakeri and Mohammad Amani and Christina Fitzmaurice and Nixon, {Molly R.} and Nooshin Abbasi and Hassan Abolhassani and Advani, {Shailesh M.} and Mohsen Afarideh and Tomi Akinyemiju and Tahiya Alam and Mahtab Alikhani and Vahid Alipour and Allen, {Christine A.} and Amir Almasi-Hashiani and Jalal Arabloo and Reza Assadi and Suleman Atique and Ashish Awasthi and Ahad Bakhtiari and Masoud Behzadifar and Kidanemaryam Berhe and Neeraj Bhala and Ali Bijani and {Bin Sayeed}, {Muhammad Shahdaat} and Tone Bj{\o}rge and Borz{\`i}, {Antonio M.} and Dejana Braithwaite and Hermann Brenner and Giulia Carreras and Felix Carvalho and Casta{\~n}eda-Orjuela, {Carlos A.} and Franz Castro and Dinh-Toi Chu and Costa, {Vera M.} and Ahmad Daryani and Davitoiu, {Dragos Virgil} and Demoz, {Gebre T.} and Demis, {Asmamaw Bizuneh} and Edgar Denova-Guti{\'e}rrez and Subhojit Dey and Nasab, {Mostafa Dianati} and Shirin Djalalinia and Emamian, {Mohammad Hassan} and Mohammad Farahmand and Fernandes, {Joāo C.} and Florian Fischer and Masoud Foroutan and Gad, {Mohamed M.} and Silvano Gallus and Gebremeskel, {Gebreamlak Gebremedhn} and Gedefew, {Getnet Azeze} and Fatemeh Ghaseni-Kebria and Giuseppe Gorini and Nima Hafezi-Nejad and Arvin Haj-Mirzaian and Haro, {Josep M.} and Harvey, {James D.} and Amir Hasanzadeh and Maryam Hashemian and Hassen, {Hamid Y.} and Hay, {Simon I.} and Hidru, {Hagos D.} and Mihaela Hostiuc and Mowafa Househ and Ilesanmi, {Olayinka Stephen} and Ilic, {Milena D.} and Kaire Innos and Farhad Islami and James, {Spencer L.} and Ensiyeh Jenabi and Rohollah Kalhor and Farin Kamangar and Amir Kasaeian and Kengne, {Andre Pascal} and Khader, {Yousef Saleh} and Rovshan Khalilov and Khan, {Ejaz Ahmad} and Gulfaraz Khan and Maryam Khayamzadeh and Maryam Khazaee-Pool and Salman Khazaei and Khoja, {Abdullah T.} and Shadmani, {Fatemah Khosravi} and Kim, {Yun Jin} and Kocarnik, {Jonathan M.} and Hamidreza Komaki and Ai Koyanagi and Vivek Kumar and {La Vecchia}, Carlo and Lopez, {Alan D.} and Raimundas Lunevicius and Navid Manafi and Ana-Laura Manda and Birhanu Geta and Hailemariam Meheretu and Getnet Mengistu and Bartosz Miazgowski and Mir, {Sayed Mostafa} and Mohammad, {Karzan Abdulmuhsin} and Mezerji, {Naser Mohammad Gholi} and Mahdi Mohammadian and Abdollah Mohammadian-Hafshejani and Reza Mohammadpourhodki and Shafiu Mohammed and Farnam Mohebi and Mokdad, {Ali H.} and Lorenzo Monasta and Mahmood Moosazadeh and Maryam Moossavi and Ghobad Moradi and Farhad Moradpour and Rahmatollah Moradzadeh and Velasquez, {Ilais Moreno} and Abbas Mosapour and Mehdi Naderi and Gurudatta Naik and Farid Najafi and Azin Nahvijou and Ionut Negoi and Rajan Nikbakhsh and Marzieh Nojomi and Olagunju, {Andrew T.} and Olagunju, {Tinuke O.} and Eyal Oren and Hadi Parsian and Cristiano Piccinelli and Akram Pourshams and Hossein Poustchi and Navid Rabiee and Amir Radfar and Alireza Rafiei and Mahdi Rahimi and Marveh Rahmati and Renzaho, {A. M. N.} and {et al}",

year = "2020",

doi = "10.1016/S2468-1253(19)30328-0",

language = "English",

volume = "5",

pages = "42--54",

journal = "The Lancet Gastroenterology and Hepatology",

issn = "2468-1253",

publisher = "The Lancet Publishing Group",

number = "1",

}

Etemadi, A, Safiri, S, Sepanlou, SG, Ikuta, K, Bisignano, C, Shakeri, R, Amani, M, Fitzmaurice, C, Nixon, MR, Abbasi, N, Abolhassani, H, Advani, SM, Afarideh, M, Akinyemiju, T, Alam, T, Alikhani, M, Alipour, V, Allen, CA, Almasi-Hashiani, A, Arabloo, J, Assadi, R, Atique, S, Awasthi, A, Bakhtiari, A, Behzadifar, M, Berhe, K, Bhala, N, Bijani, A, Bin Sayeed, MS, Bjørge, T, Borzì, AM, Braithwaite, D, Brenner, H, Carreras, G, Carvalho, F, Castañeda-Orjuela, CA, Castro, F, Chu, D-T, Costa, VM, Daryani, A, Davitoiu, DV, Demoz, GT, Demis, AB, Denova-Gutiérrez, E, Dey, S, Nasab, MD, Djalalinia, S, Emamian, MH, Farahmand, M, Fernandes, JC, Fischer, F, Foroutan, M, Gad, MM, Gallus, S, Gebremeskel, GG, Gedefew, GA, Ghaseni-Kebria, F, Gorini, G, Hafezi-Nejad, N, Haj-Mirzaian, A, Haro, JM, Harvey, JD, Hasanzadeh, A, Hashemian, M, Hassen, HY, Hay, SI, Hidru, HD, Hostiuc, M, Househ, M, Ilesanmi, OS, Ilic, MD, Innos, K, Islami, F, James, SL, Jenabi, E, Kalhor, R, Kamangar, F, Kasaeian, A, Kengne, AP, Khader, YS, Khalilov, R, Khan, EA, Khan, G, Khayamzadeh, M, Khazaee-Pool, M, Khazaei, S, Khoja, AT, Shadmani, FK, Kim, YJ, Kocarnik, JM, Komaki, H, Koyanagi, A, Kumar, V, La Vecchia, C, Lopez, AD, Lunevicius, R, Manafi, N, Manda, A-L, Geta, B, Meheretu, H, Mengistu, G, Miazgowski, B, Mir, SM, Mohammad, KA, Mezerji, NMG, Mohammadian, M, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mohammed, S, Mohebi, F, Mokdad, AH, Monasta, L, Moosazadeh, M, Moossavi, M, Moradi, G, Moradpour, F, Moradzadeh, R, Velasquez, IM, Mosapour, A, Naderi, M, Naik, G, Najafi, F, Nahvijou, A, Negoi, I, Nikbakhsh, R, Nojomi, M, Olagunju, AT, Olagunju, TO, Oren, E, Parsian, H, Piccinelli, C, Pourshams, A, Poustchi, H, Rabiee, N, Radfar, A, Rafiei, A, Rahimi, M, Rahmati, M, Renzaho, AMN & et al 2020, 'The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017', The Lancet Gastroenterology and Hepatology, vol. 5, no. 1, pp. 42-54. https://doi.org/10.1016/S2468-1253(19)30328-0

TY - JOUR

T1 - The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017

AU - Etemadi, Arash

AU - Safiri, Saeid

AU - Sepanlou, Sadaf G.

AU - Ikuta, Kevin

AU - Bisignano, Catherine

AU - Shakeri, Ramin

AU - Amani, Mohammad

AU - Fitzmaurice, Christina

AU - Nixon, Molly R.

AU - Abbasi, Nooshin

AU - Abolhassani, Hassan

AU - Advani, Shailesh M.

AU - Afarideh, Mohsen

AU - Akinyemiju, Tomi

AU - Alam, Tahiya

AU - Alikhani, Mahtab

AU - Alipour, Vahid

AU - Allen, Christine A.

AU - Almasi-Hashiani, Amir

AU - Arabloo, Jalal

AU - Assadi, Reza

AU - Atique, Suleman

AU - Awasthi, Ashish

AU - Bakhtiari, Ahad

AU - Behzadifar, Masoud

AU - Berhe, Kidanemaryam

AU - Bhala, Neeraj

AU - Bijani, Ali

AU - Bin Sayeed, Muhammad Shahdaat

AU - Bjørge, Tone

AU - Borzì, Antonio M.

AU - Braithwaite, Dejana

AU - Brenner, Hermann

AU - Carreras, Giulia

AU - Carvalho, Felix

AU - Castañeda-Orjuela, Carlos A.

AU - Castro, Franz

AU - Chu, Dinh-Toi

AU - Costa, Vera M.

AU - Daryani, Ahmad

AU - Davitoiu, Dragos Virgil

AU - Demoz, Gebre T.

AU - Demis, Asmamaw Bizuneh

AU - Denova-Gutiérrez, Edgar

AU - Dey, Subhojit

AU - Nasab, Mostafa Dianati

AU - Djalalinia, Shirin

AU - Emamian, Mohammad Hassan

AU - Farahmand, Mohammad

AU - Fernandes, Joāo C.

AU - Fischer, Florian

AU - Foroutan, Masoud

AU - Gad, Mohamed M.

AU - Gallus, Silvano

AU - Gebremeskel, Gebreamlak Gebremedhn

AU - Gedefew, Getnet Azeze

AU - Ghaseni-Kebria, Fatemeh

AU - Gorini, Giuseppe

AU - Hafezi-Nejad, Nima

AU - Haj-Mirzaian, Arvin

AU - Haro, Josep M.

AU - Harvey, James D.

AU - Hasanzadeh, Amir

AU - Hashemian, Maryam

AU - Hassen, Hamid Y.

AU - Hay, Simon I.

AU - Hidru, Hagos D.

AU - Hostiuc, Mihaela

AU - Househ, Mowafa

AU - Ilesanmi, Olayinka Stephen

AU - Ilic, Milena D.

AU - Innos, Kaire

AU - Islami, Farhad

AU - James, Spencer L.

AU - Jenabi, Ensiyeh

AU - Kalhor, Rohollah

AU - Kamangar, Farin

AU - Kasaeian, Amir

AU - Kengne, Andre Pascal

AU - Khader, Yousef Saleh

AU - Khalilov, Rovshan

AU - Khan, Ejaz Ahmad

AU - Khan, Gulfaraz

AU - Khayamzadeh, Maryam

AU - Khazaee-Pool, Maryam

AU - Khazaei, Salman

AU - Khoja, Abdullah T.

AU - Shadmani, Fatemah Khosravi

AU - Kim, Yun Jin

AU - Kocarnik, Jonathan M.

AU - Komaki, Hamidreza

AU - Koyanagi, Ai

AU - Kumar, Vivek

AU - La Vecchia, Carlo

AU - Lopez, Alan D.

AU - Lunevicius, Raimundas

AU - Manafi, Navid

AU - Manda, Ana-Laura

AU - Geta, Birhanu

AU - Meheretu, Hailemariam

AU - Mengistu, Getnet

AU - Miazgowski, Bartosz

AU - Mir, Sayed Mostafa

AU - Mohammad, Karzan Abdulmuhsin

AU - Mezerji, Naser Mohammad Gholi

AU - Mohammadian, Mahdi

AU - Mohammadian-Hafshejani, Abdollah

AU - Mohammadpourhodki, Reza

AU - Mohammed, Shafiu

AU - Mohebi, Farnam

AU - Mokdad, Ali H.

AU - Monasta, Lorenzo

AU - Moosazadeh, Mahmood

AU - Moossavi, Maryam

AU - Moradi, Ghobad

AU - Moradpour, Farhad

AU - Moradzadeh, Rahmatollah

AU - Velasquez, Ilais Moreno

AU - Mosapour, Abbas

AU - Naderi, Mehdi

AU - Naik, Gurudatta

AU - Najafi, Farid

AU - Nahvijou, Azin

AU - Negoi, Ionut

AU - Nikbakhsh, Rajan

AU - Nojomi, Marzieh

AU - Olagunju, Andrew T.

AU - Olagunju, Tinuke O.

AU - Oren, Eyal

AU - Parsian, Hadi

AU - Piccinelli, Cristiano

AU - Pourshams, Akram

AU - Poustchi, Hossein

AU - Rabiee, Navid

AU - Radfar, Amir

AU - Rafiei, Alireza

AU - Rahimi, Mahdi

AU - Rahmati, Marveh

AU - Renzaho, A. M. N.

AU - et al, null

PY - 2020

Y1 - 2020

N2 - Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1Â·22 million (95% UI 1Â·19–1Â·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19Â·1 million (18Â·7–19Â·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29Â·5, 28Â·2–31Â·0 per 100 000 population) and east Asia (28Â·6, 27Â·3–30Â·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38Â·2% (21Â·1–57Â·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24Â·5% (20Â·0–28Â·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation.

AB - Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1Â·22 million (95% UI 1Â·19–1Â·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19Â·1 million (18Â·7–19Â·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29Â·5, 28Â·2–31Â·0 per 100 000 population) and east Asia (28Â·6, 27Â·3–30Â·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38Â·2% (21Â·1–57Â·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24Â·5% (20Â·0–28Â·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation.

KW - cancer

KW - disabilities

KW - mortility

KW - stomach

UR - http://hdl.handle.net/1959.7/uws:55645

U2 - 10.1016/S2468-1253(19)30328-0

DO - 10.1016/S2468-1253(19)30328-0

M3 - Article

SN - 2468-1253

VL - 5

SP - 42

EP - 54

JO - The Lancet Gastroenterology and Hepatology

JF - The Lancet Gastroenterology and Hepatology

IS - 1

ER -

The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017

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