The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh

Tanvir Abir; Felix Akpojene Ogbo; Garry John Stevens; Andrew Nicolas Page; Abul Hasnat Milton; Kingsley Emwinyore Agho

The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh

Tanvir Abir, Felix Akpojene Ogbo, Garry John Stevens, Andrew Nicolas Page, Abul Hasnat Milton, Kingsley Emwinyore Agho

Western Sydney University

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Background Appropriate antenatal care (ANC) is an important preventive public health intervention to ensure women's and newborn health outcomes. The study aimed to investigate the impact of ANC, ironÂ±folic acid (IFA) supplementation and tetanus toxoid (TT) vaccination during pregnancy on child mortality in Bangladesh. Method A cross-sectional study of three datasets from the Bangladesh Demographic and Health Surveys for the years 2004, 2007 and 2011 were pooled and used for the analyses. A total weighted sample of 16,721 maternal responses (5,364 for 2004; 4,872 for 2007 and 6,485 for 2011) was used. Multivariate logistic models that adjusted for cluster and sampling weights were used to examine the impact of ANC, IFA supplementation and TT vaccination during pregnancy on the death of a child aged 0Â±28 days (neonatal), 1Â±11 months (post-neonatal) and 12Â±59 months (child). Results Multivariable analyses revealed that the odds of postnatal and under-5 mortality was lower in mothers who had ANC [Odds Ratio (OR) = 0.60, 95% confidence interval (95% CI): 0.43Â±0.85], IFA supplementation [OR = 0.66, 95% CI: (0.45Â±0.98)] and _2 TT vaccinations (OR = 0.43, 95% CI: 0.49Â±0.78) for post-natal mortality; and for under-5 mortality, any form of ANC (OR = 0.69, 95% CI: 0.51Â±0.93), IFA supplementation (OR = 0.67, 95% CI: 0.48Â± 0.94) and _2 TT vaccinations (OR = 0.50, 95% CI: 0.36Â±0.69). When combined, TT vaccination with IFA supplementation, and TT vaccination without IFA supplementation were protective across all groups. Conclusion The study found that ANC, IFA supplementation, and TT vaccination during pregnancy reduced the likelihood of child mortality in Bangladesh. The findings suggest that considerable gains in improving child survival could be achieved through ensuring universal coverage of ANC, promoting TT vaccination during pregnancy and IFA supplementation among pregnant women in Bangladesh.

Original language	English
Article number	e0187090
Number of pages	14
Journal	PLoS One
Volume	12
Issue number	11
Publication status	Published - Nov 2017

Bibliographical note

Publisher Copyright:
© 2017 Abir et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Open Access - Access Right Statement

© 2017 Abir et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Keywords

Bangladesh
children
folic acid
mortality
pregnancy
prenatal care
tetanus
vaccination

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@article{2667b343fd2848a7acf27ec90c2d9946,

title = "The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh",

abstract = "Background Appropriate antenatal care (ANC) is an important preventive public health intervention to ensure women's and newborn health outcomes. The study aimed to investigate the impact of ANC, iron{\^A}±folic acid (IFA) supplementation and tetanus toxoid (TT) vaccination during pregnancy on child mortality in Bangladesh. Method A cross-sectional study of three datasets from the Bangladesh Demographic and Health Surveys for the years 2004, 2007 and 2011 were pooled and used for the analyses. A total weighted sample of 16,721 maternal responses (5,364 for 2004; 4,872 for 2007 and 6,485 for 2011) was used. Multivariate logistic models that adjusted for cluster and sampling weights were used to examine the impact of ANC, IFA supplementation and TT vaccination during pregnancy on the death of a child aged 0{\^A}±28 days (neonatal), 1{\^A}±11 months (post-neonatal) and 12{\^A}±59 months (child). Results Multivariable analyses revealed that the odds of postnatal and under-5 mortality was lower in mothers who had ANC [Odds Ratio (OR) = 0.60, 95% confidence interval (95% CI): 0.43{\^A}±0.85], IFA supplementation [OR = 0.66, 95% CI: (0.45{\^A}±0.98)] and _2 TT vaccinations (OR = 0.43, 95% CI: 0.49{\^A}±0.78) for post-natal mortality; and for under-5 mortality, any form of ANC (OR = 0.69, 95% CI: 0.51{\^A}±0.93), IFA supplementation (OR = 0.67, 95% CI: 0.48{\^A}± 0.94) and _2 TT vaccinations (OR = 0.50, 95% CI: 0.36{\^A}±0.69). When combined, TT vaccination with IFA supplementation, and TT vaccination without IFA supplementation were protective across all groups. Conclusion The study found that ANC, IFA supplementation, and TT vaccination during pregnancy reduced the likelihood of child mortality in Bangladesh. The findings suggest that considerable gains in improving child survival could be achieved through ensuring universal coverage of ANC, promoting TT vaccination during pregnancy and IFA supplementation among pregnant women in Bangladesh.",

keywords = "Bangladesh, children, folic acid, mortality, pregnancy, prenatal care, tetanus, vaccination",

author = "Tanvir Abir and Ogbo, {Felix Akpojene} and Stevens, {Garry John} and Page, {Andrew Nicolas} and Milton, {Abul Hasnat} and Agho, {Kingsley Emwinyore}",

note = "Publisher Copyright: {\textcopyright} 2017 Abir et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2017",

month = nov,

language = "English",

volume = "12",

journal = "PLoS One",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "11",

}

TY - JOUR

T1 - The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh

AU - Abir, Tanvir

AU - Ogbo, Felix Akpojene

AU - Stevens, Garry John

AU - Page, Andrew Nicolas

AU - Milton, Abul Hasnat

AU - Agho, Kingsley Emwinyore

N1 - Publisher Copyright: © 2017 Abir et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2017/11

Y1 - 2017/11

N2 - Background Appropriate antenatal care (ANC) is an important preventive public health intervention to ensure women's and newborn health outcomes. The study aimed to investigate the impact of ANC, ironÂ±folic acid (IFA) supplementation and tetanus toxoid (TT) vaccination during pregnancy on child mortality in Bangladesh. Method A cross-sectional study of three datasets from the Bangladesh Demographic and Health Surveys for the years 2004, 2007 and 2011 were pooled and used for the analyses. A total weighted sample of 16,721 maternal responses (5,364 for 2004; 4,872 for 2007 and 6,485 for 2011) was used. Multivariate logistic models that adjusted for cluster and sampling weights were used to examine the impact of ANC, IFA supplementation and TT vaccination during pregnancy on the death of a child aged 0Â±28 days (neonatal), 1Â±11 months (post-neonatal) and 12Â±59 months (child). Results Multivariable analyses revealed that the odds of postnatal and under-5 mortality was lower in mothers who had ANC [Odds Ratio (OR) = 0.60, 95% confidence interval (95% CI): 0.43Â±0.85], IFA supplementation [OR = 0.66, 95% CI: (0.45Â±0.98)] and _2 TT vaccinations (OR = 0.43, 95% CI: 0.49Â±0.78) for post-natal mortality; and for under-5 mortality, any form of ANC (OR = 0.69, 95% CI: 0.51Â±0.93), IFA supplementation (OR = 0.67, 95% CI: 0.48Â± 0.94) and _2 TT vaccinations (OR = 0.50, 95% CI: 0.36Â±0.69). When combined, TT vaccination with IFA supplementation, and TT vaccination without IFA supplementation were protective across all groups. Conclusion The study found that ANC, IFA supplementation, and TT vaccination during pregnancy reduced the likelihood of child mortality in Bangladesh. The findings suggest that considerable gains in improving child survival could be achieved through ensuring universal coverage of ANC, promoting TT vaccination during pregnancy and IFA supplementation among pregnant women in Bangladesh.

AB - Background Appropriate antenatal care (ANC) is an important preventive public health intervention to ensure women's and newborn health outcomes. The study aimed to investigate the impact of ANC, ironÂ±folic acid (IFA) supplementation and tetanus toxoid (TT) vaccination during pregnancy on child mortality in Bangladesh. Method A cross-sectional study of three datasets from the Bangladesh Demographic and Health Surveys for the years 2004, 2007 and 2011 were pooled and used for the analyses. A total weighted sample of 16,721 maternal responses (5,364 for 2004; 4,872 for 2007 and 6,485 for 2011) was used. Multivariate logistic models that adjusted for cluster and sampling weights were used to examine the impact of ANC, IFA supplementation and TT vaccination during pregnancy on the death of a child aged 0Â±28 days (neonatal), 1Â±11 months (post-neonatal) and 12Â±59 months (child). Results Multivariable analyses revealed that the odds of postnatal and under-5 mortality was lower in mothers who had ANC [Odds Ratio (OR) = 0.60, 95% confidence interval (95% CI): 0.43Â±0.85], IFA supplementation [OR = 0.66, 95% CI: (0.45Â±0.98)] and _2 TT vaccinations (OR = 0.43, 95% CI: 0.49Â±0.78) for post-natal mortality; and for under-5 mortality, any form of ANC (OR = 0.69, 95% CI: 0.51Â±0.93), IFA supplementation (OR = 0.67, 95% CI: 0.48Â± 0.94) and _2 TT vaccinations (OR = 0.50, 95% CI: 0.36Â±0.69). When combined, TT vaccination with IFA supplementation, and TT vaccination without IFA supplementation were protective across all groups. Conclusion The study found that ANC, IFA supplementation, and TT vaccination during pregnancy reduced the likelihood of child mortality in Bangladesh. The findings suggest that considerable gains in improving child survival could be achieved through ensuring universal coverage of ANC, promoting TT vaccination during pregnancy and IFA supplementation among pregnant women in Bangladesh.

KW - Bangladesh

KW - children

KW - folic acid

KW - mortality

KW - pregnancy

KW - prenatal care

KW - tetanus

KW - vaccination

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:44069

M3 - Article

SN - 1932-6203

VL - 12

JO - PLoS One

JF - PLoS One

IS - 11

M1 - e0187090

ER -

The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh

Abstract

Bibliographical note

Open Access - Access Right Statement

Keywords

UN SDGs

Other files and links

Fingerprint

Cite this