The physiological stress response to high-intensity sprint exercise following the ingestion of sodium bicarbonate

Daniel J. Peart; Richard J. Kirk; Angela R. Hillman; Leigh A. Madden; Jason C. Siegler; Rebecca V. Vince

doi:10.1007/s00421-012-2419-4

The physiological stress response to high-intensity sprint exercise following the ingestion of sodium bicarbonate

Daniel J. Peart, Richard J. Kirk, Angela R. Hillman, Leigh A. Madden, Jason C. Siegler, Rebecca V. Vince

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of this study was to investigate the effects of pre-exercise alkalosis on the physiological stress response to high-intensity exercise. Seven physically active males (age 22 +/- A 3 years, height 1.82 +/- A 0.06 m, mass 81.3 +/- A 8.4 kg and peak power output 300 +/- A 22 W) performed a repeated sprint cycle exercise following a dose of 0.3 g kg(-1) body mass of sodium bicarbonate (NaHCO3) (BICARB), or a placebo of 0.045 g kg(-1) body mass of sodium chloride (PLAC). Monocyte-expressed heat shock protein 72 (HSP72) and plasma thiobarbituric acid reactive substances (TBARS) were significantly attenuated in BICARB compared to PLAC (p = 0.04 and p = 0.039, respectively), however total anti-oxidant capacity, the ratio of oxidised to total glutathione, cortisol, interleukin 6 and interleukin 8 were not significantly induced by the exercise. In conclusion, monocyte-expressed HSP72 is significantly increased following high-intensity anaerobic exercise, and its attenuation following such exercise with the ingestion of NaHCO3 is unlikely to be due to a decreased oxidative stress.

Original language	English
Pages (from-to)	127-134
Number of pages	8
Journal	European Journal of Applied Physiology
Volume	113
Issue number	1
DOIs	https://doi.org/10.1007/s00421-012-2419-4
Publication status	Published - 2013

Keywords

alkalosis
anaerobic exercise
heat shock
oxidative stress
performance
racing time
supplementation

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10.1007/s00421-012-2419-4

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title = "The physiological stress response to high-intensity sprint exercise following the ingestion of sodium bicarbonate",

abstract = "The purpose of this study was to investigate the effects of pre-exercise alkalosis on the physiological stress response to high-intensity exercise. Seven physically active males (age 22 +/- A 3 years, height 1.82 +/- A 0.06 m, mass 81.3 +/- A 8.4 kg and peak power output 300 +/- A 22 W) performed a repeated sprint cycle exercise following a dose of 0.3 g kg(-1) body mass of sodium bicarbonate (NaHCO3) (BICARB), or a placebo of 0.045 g kg(-1) body mass of sodium chloride (PLAC). Monocyte-expressed heat shock protein 72 (HSP72) and plasma thiobarbituric acid reactive substances (TBARS) were significantly attenuated in BICARB compared to PLAC (p = 0.04 and p = 0.039, respectively), however total anti-oxidant capacity, the ratio of oxidised to total glutathione, cortisol, interleukin 6 and interleukin 8 were not significantly induced by the exercise. In conclusion, monocyte-expressed HSP72 is significantly increased following high-intensity anaerobic exercise, and its attenuation following such exercise with the ingestion of NaHCO3 is unlikely to be due to a decreased oxidative stress.",

keywords = "alkalosis, anaerobic exercise, heat shock, oxidative stress, performance, racing time, supplementation",

author = "Peart, {Daniel J.} and Kirk, {Richard J.} and Hillman, {Angela R.} and Madden, {Leigh A.} and Siegler, {Jason C.} and Vince, {Rebecca V.}",

year = "2013",

doi = "10.1007/s00421-012-2419-4",

language = "English",

volume = "113",

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journal = "European Journal of Applied Physiology",

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T1 - The physiological stress response to high-intensity sprint exercise following the ingestion of sodium bicarbonate

AU - Peart, Daniel J.

AU - Kirk, Richard J.

AU - Hillman, Angela R.

AU - Madden, Leigh A.

AU - Siegler, Jason C.

AU - Vince, Rebecca V.

PY - 2013

Y1 - 2013

N2 - The purpose of this study was to investigate the effects of pre-exercise alkalosis on the physiological stress response to high-intensity exercise. Seven physically active males (age 22 +/- A 3 years, height 1.82 +/- A 0.06 m, mass 81.3 +/- A 8.4 kg and peak power output 300 +/- A 22 W) performed a repeated sprint cycle exercise following a dose of 0.3 g kg(-1) body mass of sodium bicarbonate (NaHCO3) (BICARB), or a placebo of 0.045 g kg(-1) body mass of sodium chloride (PLAC). Monocyte-expressed heat shock protein 72 (HSP72) and plasma thiobarbituric acid reactive substances (TBARS) were significantly attenuated in BICARB compared to PLAC (p = 0.04 and p = 0.039, respectively), however total anti-oxidant capacity, the ratio of oxidised to total glutathione, cortisol, interleukin 6 and interleukin 8 were not significantly induced by the exercise. In conclusion, monocyte-expressed HSP72 is significantly increased following high-intensity anaerobic exercise, and its attenuation following such exercise with the ingestion of NaHCO3 is unlikely to be due to a decreased oxidative stress.

AB - The purpose of this study was to investigate the effects of pre-exercise alkalosis on the physiological stress response to high-intensity exercise. Seven physically active males (age 22 +/- A 3 years, height 1.82 +/- A 0.06 m, mass 81.3 +/- A 8.4 kg and peak power output 300 +/- A 22 W) performed a repeated sprint cycle exercise following a dose of 0.3 g kg(-1) body mass of sodium bicarbonate (NaHCO3) (BICARB), or a placebo of 0.045 g kg(-1) body mass of sodium chloride (PLAC). Monocyte-expressed heat shock protein 72 (HSP72) and plasma thiobarbituric acid reactive substances (TBARS) were significantly attenuated in BICARB compared to PLAC (p = 0.04 and p = 0.039, respectively), however total anti-oxidant capacity, the ratio of oxidised to total glutathione, cortisol, interleukin 6 and interleukin 8 were not significantly induced by the exercise. In conclusion, monocyte-expressed HSP72 is significantly increased following high-intensity anaerobic exercise, and its attenuation following such exercise with the ingestion of NaHCO3 is unlikely to be due to a decreased oxidative stress.

KW - alkalosis

KW - anaerobic exercise

KW - heat shock

KW - oxidative stress

KW - performance

KW - racing time

KW - supplementation

UR - http://handle.uws.edu.au:8081/1959.7/524563

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DO - 10.1007/s00421-012-2419-4

M3 - Article

SN - 1439-6327

SN - 1439-6319

VL - 113

SP - 127

EP - 134

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

IS - 1

ER -

The physiological stress response to high-intensity sprint exercise following the ingestion of sodium bicarbonate

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Keywords

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