Tissue repair strength using chitosan adhesives with different physical-chemical characteristics

Matthew J. Barton; John W. Morley; David A. Mahns; Damia Mawad; Richard Wuhrer; David Fania; Samuel J. Frost; Christian Loebbe; Antonio Lauto

doi:10.1002/jbio.201300148

Tissue repair strength using chitosan adhesives with different physical-chemical characteristics

Matthew J. Barton, John W. Morley, David A. Mahns, Damia Mawad, Richard Wuhrer, David Fania, Samuel J. Frost, Christian Loebbe, Antonio Lauto

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

A range of chitosan-based biomaterials have recently been used to perform sutureless, laser-activated tissue repair. Laser-activation has the advantage of bonding to tissue through a non-contact, aseptic mechanism. Chitosan adhesive films have also been shown to adhere to sheep intestine strongly without any chemical modification to chitosan. In this study, we continue to investigate chitosan adhesive films and explore the impact on the tissue repair strength and tensile strength characteristics of four types of adhesive film based on chitosan with different molecular weight and degree of deacetylation. Results showed that adhesives based on chitosan with medium molecular weight achieved the highest bonding strength, tensile strength and E-modulus when compared to the other adhesives.

Original language	English
Pages (from-to)	948-955
Number of pages	8
Journal	Journal of Biophotonics
Volume	7
Issue number	45637
DOIs	https://doi.org/10.1002/jbio.201300148
Publication status	Published - 2014

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title = "Tissue repair strength using chitosan adhesives with different physical-chemical characteristics",

abstract = "A range of chitosan-based biomaterials have recently been used to perform sutureless, laser-activated tissue repair. Laser-activation has the advantage of bonding to tissue through a non-contact, aseptic mechanism. Chitosan adhesive films have also been shown to adhere to sheep intestine strongly without any chemical modification to chitosan. In this study, we continue to investigate chitosan adhesive films and explore the impact on the tissue repair strength and tensile strength characteristics of four types of adhesive film based on chitosan with different molecular weight and degree of deacetylation. Results showed that adhesives based on chitosan with medium molecular weight achieved the highest bonding strength, tensile strength and E-modulus when compared to the other adhesives.",

author = "Barton, {Matthew J.} and Morley, {John W.} and Mahns, {David A.} and Damia Mawad and Richard Wuhrer and David Fania and Frost, {Samuel J.} and Christian Loebbe and Antonio Lauto",

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language = "English",

volume = "7",

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T1 - Tissue repair strength using chitosan adhesives with different physical-chemical characteristics

AU - Barton, Matthew J.

AU - Morley, John W.

AU - Mahns, David A.

AU - Mawad, Damia

AU - Wuhrer, Richard

AU - Fania, David

AU - Frost, Samuel J.

AU - Loebbe, Christian

AU - Lauto, Antonio

PY - 2014

Y1 - 2014

N2 - A range of chitosan-based biomaterials have recently been used to perform sutureless, laser-activated tissue repair. Laser-activation has the advantage of bonding to tissue through a non-contact, aseptic mechanism. Chitosan adhesive films have also been shown to adhere to sheep intestine strongly without any chemical modification to chitosan. In this study, we continue to investigate chitosan adhesive films and explore the impact on the tissue repair strength and tensile strength characteristics of four types of adhesive film based on chitosan with different molecular weight and degree of deacetylation. Results showed that adhesives based on chitosan with medium molecular weight achieved the highest bonding strength, tensile strength and E-modulus when compared to the other adhesives.

AB - A range of chitosan-based biomaterials have recently been used to perform sutureless, laser-activated tissue repair. Laser-activation has the advantage of bonding to tissue through a non-contact, aseptic mechanism. Chitosan adhesive films have also been shown to adhere to sheep intestine strongly without any chemical modification to chitosan. In this study, we continue to investigate chitosan adhesive films and explore the impact on the tissue repair strength and tensile strength characteristics of four types of adhesive film based on chitosan with different molecular weight and degree of deacetylation. Results showed that adhesives based on chitosan with medium molecular weight achieved the highest bonding strength, tensile strength and E-modulus when compared to the other adhesives.

UR - http://hdl.handle.net/1959.7/uws:27422

U2 - 10.1002/jbio.201300148

DO - 10.1002/jbio.201300148

M3 - Article

SN - 1864-063X

VL - 7

SP - 948

EP - 955

JO - Journal of Biophotonics

JF - Journal of Biophotonics

IS - 45637

ER -

Tissue repair strength using chitosan adhesives with different physical-chemical characteristics

Abstract

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