Toll-like receptors, innate immune system, and lung diseases: a vital trilateral association

Vyoma K. Patel; Keshav R. Paudel; Shakti D. Shukla; Gang Liu; Brian G. Oliver; Philip M. Hansbro; Kamal Dua

doi:10.17179/excli2022-4688

Toll-like receptors, innate immune system, and lung diseases: a vital trilateral association

Vyoma K. Patel
, Keshav R. Paudel
, Shakti D. Shukla
, Gang Liu
, Brian G. Oliver
, Philip M. Hansbro
, Kamal Dua

Macular Disease Foundation Australia
University of Technology Sydney
Centenary Institute
University of Sydney

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

1 Downloads (Pure)

Abstract

The lung is highly susceptible to external environmental pollutants such as infectious agents and foreign antigens and thus, expresses an extensive repertoire of pathogen recognition recep-tors (PRRs) to recognize both exogenous pathogen-associated and endogenous danger-associ-ated molecular patterns (Jiang et al., 2006, Lipinski et al., 2021). Notably, Toll-like receptors (TLR) play a key role in this process as they are located on cell surface as well as intracellularly (Lipinski et al., 2021; Maris et al., 2006).

Original language	English
Pages (from-to)	519-523
Number of pages	5
Journal	EXCLI Journal
Volume	21
DOIs	https://doi.org/10.17179/excli2022-4688
Publication status	Published - Jan 2022
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.17179/excli2022-4688Licence: CC BY

Full textFinal published version, 399 KBLicence: CC BY

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title = "Toll-like receptors, innate immune system, and lung diseases: a vital trilateral association",

abstract = "The lung is highly susceptible to external environmental pollutants such as infectious agents and foreign antigens and thus, expresses an extensive repertoire of pathogen recognition recep-tors (PRRs) to recognize both exogenous pathogen-associated and endogenous danger-associ-ated molecular patterns (Jiang et al., 2006, Lipinski et al., 2021). Notably, Toll-like receptors (TLR) play a key role in this process as they are located on cell surface as well as intracellularly (Lipinski et al., 2021; Maris et al., 2006).",

author = "Patel, \{Vyoma K.\} and Paudel, \{Keshav R.\} and Shukla, \{Shakti D.\} and Gang Liu and Oliver, \{Brian G.\} and Hansbro, \{Philip M.\} and Kamal Dua",

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T1 - Toll-like receptors, innate immune system, and lung diseases

T2 - a vital trilateral association

AU - Patel, Vyoma K.

AU - Paudel, Keshav R.

AU - Shukla, Shakti D.

AU - Liu, Gang

AU - Oliver, Brian G.

AU - Hansbro, Philip M.

AU - Dua, Kamal

PY - 2022/1

Y1 - 2022/1

N2 - The lung is highly susceptible to external environmental pollutants such as infectious agents and foreign antigens and thus, expresses an extensive repertoire of pathogen recognition recep-tors (PRRs) to recognize both exogenous pathogen-associated and endogenous danger-associ-ated molecular patterns (Jiang et al., 2006, Lipinski et al., 2021). Notably, Toll-like receptors (TLR) play a key role in this process as they are located on cell surface as well as intracellularly (Lipinski et al., 2021; Maris et al., 2006).

AB - The lung is highly susceptible to external environmental pollutants such as infectious agents and foreign antigens and thus, expresses an extensive repertoire of pathogen recognition recep-tors (PRRs) to recognize both exogenous pathogen-associated and endogenous danger-associ-ated molecular patterns (Jiang et al., 2006, Lipinski et al., 2021). Notably, Toll-like receptors (TLR) play a key role in this process as they are located on cell surface as well as intracellularly (Lipinski et al., 2021; Maris et al., 2006).

UR - https://www.scopus.com/pages/publications/85125574982

U2 - 10.17179/excli2022-4688

DO - 10.17179/excli2022-4688

M3 - Article

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VL - 21

SP - 519

EP - 523

JO - EXCLI Journal

JF - EXCLI Journal

ER -

Toll-like receptors, innate immune system, and lung diseases: a vital trilateral association

Abstract

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