Treatments used for obsessive-compulsive disorder : an international perspective

Vlasios Brakoulias; Vladan Starcevic; Umberto Albert; Shyam Sundar Arumugham; Brenda E. Bailey; Amparo Belloch; Tania Borda; Liliana Dell'Osso; Jason A. Elias; Martha J. Falkenstein; Ygor A. Ferrao; Leonardo F. Fontenelle; Lena Jelinek; Leto Kalogeraki; Brian Kay; Luana D. Laurito; Christine Lochner; Giuseppe Maina; Donatella Marazziti; Andrew Martin; Hisato Matsunaga; Euripedes C. Miguel; Pedro Morgado; Irakis Mourikis; Massimo Pasquini; Rodrigo Perez Rivera; Sriramya Potluri; Janardhan Y. C. Reddy; Brian C. Riemann; Maria Conceição do Rosario; Roseli G. Shavitt; Dan J. Stein; Kirupumani Viswasam; Zhen Wang; Naomi A. Fineberg

doi:10.1002/hup.2686

Treatments used for obsessive-compulsive disorder : an international perspective

Vlasios Brakoulias, Vladan Starcevic, Umberto Albert, Shyam Sundar Arumugham, Brenda E. Bailey, Amparo Belloch, Tania Borda, Liliana Dell'Osso, Jason A. Elias, Martha J. Falkenstein, Ygor A. Ferrao, Leonardo F. Fontenelle, Lena Jelinek, Leto Kalogeraki, Brian Kay, Luana D. Laurito, Christine Lochner, Giuseppe Maina, Donatella Marazziti, Andrew MartinHisato Matsunaga, Euripedes C. Miguel, Pedro Morgado, Irakis Mourikis, Massimo Pasquini, Rodrigo Perez Rivera, Sriramya Potluri, Janardhan Y. C. Reddy, Brian C. Riemann, Maria Conceição do Rosario, Roseli G. Shavitt, Dan J. Stein, Kirupumani Viswasam, Zhen Wang, Naomi A. Fineberg

Western Sydney University

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Methods: Researchers in the field of OCD were invited to contribute summary statistics on the characteristics of their samples. Consistency of summary statistics across countries was evaluated. Results: The study surveyed 19 expert centres from 15 countries (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, the United Kingdom, and the United States) providing a total sample of 7,340 participants. Fluoxetine (n = 972; 13.2%) and fluvoxamine (n = 913; 12.4%) were the most commonly used selective serotonin reuptake inhibitor medications. Risperidone (n = 428; 7.3%) and aripiprazole (n = 415; 7.1%) were the most commonly used antipsychotic agents. Neurostimulation techniques such as transcranial magnetic stimulation, deep brain stimulation, gamma knife surgery, and psychosurgery were used in less than 1% of the sample. There was significant variation in the use and accessibility of exposure and response prevention for OCD. Conclusions: The variation between countries in treatments used for OCD needs further evaluation. Exposure and response prevention is not used as frequently as guidelines suggest and appears difficult to access in most countries. Updated treatment guidelines are recommended.

Original language	English
Article number	e2686
Number of pages	10
Journal	Human Psychopharmacology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1002/hup.2686
Publication status	Published - 2019

Keywords

antipsychotic drugs
obsessive, compulsive disorder
therapeutics

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10.1002/hup.2686

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Brakoulias, V., Starcevic, V., Albert, U., Arumugham, S. S., Bailey, B. E., Belloch, A., Borda, T., Dell'Osso, L., Elias, J. A., Falkenstein, M. J., Ferrao, Y. A., Fontenelle, L. F., Jelinek, L., Kalogeraki, L., Kay, B., Laurito, L. D., Lochner, C., Maina, G., Marazziti, D., ... Fineberg, N. A. (2019). Treatments used for obsessive-compulsive disorder : an international perspective. Human Psychopharmacology, 34(1), Article e2686. https://doi.org/10.1002/hup.2686

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title = "Treatments used for obsessive-compulsive disorder : an international perspective",

abstract = "Methods: Researchers in the field of OCD were invited to contribute summary statistics on the characteristics of their samples. Consistency of summary statistics across countries was evaluated. Results: The study surveyed 19 expert centres from 15 countries (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, the United Kingdom, and the United States) providing a total sample of 7,340 participants. Fluoxetine (n = 972; 13.2%) and fluvoxamine (n = 913; 12.4%) were the most commonly used selective serotonin reuptake inhibitor medications. Risperidone (n = 428; 7.3%) and aripiprazole (n = 415; 7.1%) were the most commonly used antipsychotic agents. Neurostimulation techniques such as transcranial magnetic stimulation, deep brain stimulation, gamma knife surgery, and psychosurgery were used in less than 1% of the sample. There was significant variation in the use and accessibility of exposure and response prevention for OCD. Conclusions: The variation between countries in treatments used for OCD needs further evaluation. Exposure and response prevention is not used as frequently as guidelines suggest and appears difficult to access in most countries. Updated treatment guidelines are recommended.",

keywords = "antipsychotic drugs, obsessive, compulsive disorder, therapeutics",

author = "Vlasios Brakoulias and Vladan Starcevic and Umberto Albert and Arumugham, {Shyam Sundar} and Bailey, {Brenda E.} and Amparo Belloch and Tania Borda and Liliana Dell'Osso and Elias, {Jason A.} and Falkenstein, {Martha J.} and Ferrao, {Ygor A.} and Fontenelle, {Leonardo F.} and Lena Jelinek and Leto Kalogeraki and Brian Kay and Laurito, {Luana D.} and Christine Lochner and Giuseppe Maina and Donatella Marazziti and Andrew Martin and Hisato Matsunaga and Miguel, {Euripedes C.} and Pedro Morgado and Irakis Mourikis and Massimo Pasquini and {Perez Rivera}, Rodrigo and Sriramya Potluri and Reddy, {Janardhan Y. C.} and Riemann, {Brian C.} and {do Rosario}, {Maria Concei{\c c}{\~a}o} and Shavitt, {Roseli G.} and Stein, {Dan J.} and Kirupumani Viswasam and Zhen Wang and Fineberg, {Naomi A.}",

year = "2019",

doi = "10.1002/hup.2686",

language = "English",

volume = "34",

journal = "Human Psychopharmacology",

issn = "0885-6222",

publisher = "John Wiley & Sons",

number = "1",

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Brakoulias, V, Starcevic, V, Albert, U, Arumugham, SS, Bailey, BE, Belloch, A, Borda, T, Dell'Osso, L, Elias, JA, Falkenstein, MJ, Ferrao, YA, Fontenelle, LF, Jelinek, L, Kalogeraki, L, Kay, B, Laurito, LD, Lochner, C, Maina, G, Marazziti, D, Martin, A, Matsunaga, H, Miguel, EC, Morgado, P, Mourikis, I, Pasquini, M, Perez Rivera, R, Potluri, S, Reddy, JYC, Riemann, BC, do Rosario, MC, Shavitt, RG, Stein, DJ, Viswasam, K, Wang, Z & Fineberg, NA 2019, 'Treatments used for obsessive-compulsive disorder : an international perspective', Human Psychopharmacology, vol. 34, no. 1, e2686. https://doi.org/10.1002/hup.2686

TY - JOUR

T1 - Treatments used for obsessive-compulsive disorder : an international perspective

AU - Brakoulias, Vlasios

AU - Starcevic, Vladan

AU - Albert, Umberto

AU - Arumugham, Shyam Sundar

AU - Bailey, Brenda E.

AU - Belloch, Amparo

AU - Borda, Tania

AU - Dell'Osso, Liliana

AU - Elias, Jason A.

AU - Falkenstein, Martha J.

AU - Ferrao, Ygor A.

AU - Fontenelle, Leonardo F.

AU - Jelinek, Lena

AU - Kalogeraki, Leto

AU - Kay, Brian

AU - Laurito, Luana D.

AU - Lochner, Christine

AU - Maina, Giuseppe

AU - Marazziti, Donatella

AU - Martin, Andrew

AU - Matsunaga, Hisato

AU - Miguel, Euripedes C.

AU - Morgado, Pedro

AU - Mourikis, Irakis

AU - Pasquini, Massimo

AU - Perez Rivera, Rodrigo

AU - Potluri, Sriramya

AU - Reddy, Janardhan Y. C.

AU - Riemann, Brian C.

AU - do Rosario, Maria Conceição

AU - Shavitt, Roseli G.

AU - Stein, Dan J.

AU - Viswasam, Kirupumani

AU - Wang, Zhen

AU - Fineberg, Naomi A.

PY - 2019

Y1 - 2019

N2 - Methods: Researchers in the field of OCD were invited to contribute summary statistics on the characteristics of their samples. Consistency of summary statistics across countries was evaluated. Results: The study surveyed 19 expert centres from 15 countries (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, the United Kingdom, and the United States) providing a total sample of 7,340 participants. Fluoxetine (n = 972; 13.2%) and fluvoxamine (n = 913; 12.4%) were the most commonly used selective serotonin reuptake inhibitor medications. Risperidone (n = 428; 7.3%) and aripiprazole (n = 415; 7.1%) were the most commonly used antipsychotic agents. Neurostimulation techniques such as transcranial magnetic stimulation, deep brain stimulation, gamma knife surgery, and psychosurgery were used in less than 1% of the sample. There was significant variation in the use and accessibility of exposure and response prevention for OCD. Conclusions: The variation between countries in treatments used for OCD needs further evaluation. Exposure and response prevention is not used as frequently as guidelines suggest and appears difficult to access in most countries. Updated treatment guidelines are recommended.

AB - Methods: Researchers in the field of OCD were invited to contribute summary statistics on the characteristics of their samples. Consistency of summary statistics across countries was evaluated. Results: The study surveyed 19 expert centres from 15 countries (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, the United Kingdom, and the United States) providing a total sample of 7,340 participants. Fluoxetine (n = 972; 13.2%) and fluvoxamine (n = 913; 12.4%) were the most commonly used selective serotonin reuptake inhibitor medications. Risperidone (n = 428; 7.3%) and aripiprazole (n = 415; 7.1%) were the most commonly used antipsychotic agents. Neurostimulation techniques such as transcranial magnetic stimulation, deep brain stimulation, gamma knife surgery, and psychosurgery were used in less than 1% of the sample. There was significant variation in the use and accessibility of exposure and response prevention for OCD. Conclusions: The variation between countries in treatments used for OCD needs further evaluation. Exposure and response prevention is not used as frequently as guidelines suggest and appears difficult to access in most countries. Updated treatment guidelines are recommended.

KW - antipsychotic drugs

KW - obsessive, compulsive disorder

KW - therapeutics

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:50454

U2 - 10.1002/hup.2686

DO - 10.1002/hup.2686

M3 - Article

SN - 0885-6222

VL - 34

JO - Human Psychopharmacology

JF - Human Psychopharmacology

IS - 1

M1 - e2686

ER -

Treatments used for obsessive-compulsive disorder : an international perspective

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Keywords

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