TY - JOUR
T1 - Triangulation of methods using insect cell lines to investigate insecticidal mode-of-action
AU - Mak, Michelle
AU - Beattie, Karren D.
AU - Basta, Albert
AU - Randall, David
AU - Chen, Zhong-Hua
AU - Spooner-Hart, Robert
PY - 2021
Y1 - 2021
N2 - This study investigated three in vitro models to assist in elucidating possible mode‐of‐action, which could be adopted to evaluate insecticidal activity of complex, unknown, or multi‐constituent formulations. We used a combination of absorbance spectrometry, confocal scanning laser microscopy and microelectrode ion flux estimation (MIFE) to provide insight into potential target sites for insecticides. This study used two insect cell lines and evaluated three pyrethroid insecticides.
AB - This study investigated three in vitro models to assist in elucidating possible mode‐of‐action, which could be adopted to evaluate insecticidal activity of complex, unknown, or multi‐constituent formulations. We used a combination of absorbance spectrometry, confocal scanning laser microscopy and microelectrode ion flux estimation (MIFE) to provide insight into potential target sites for insecticides. This study used two insect cell lines and evaluated three pyrethroid insecticides.
KW - botanical pesticides
KW - insect cell biotechnology
UR - https://hdl.handle.net/1959.7/uws:58762
U2 - 10.1002/ps.6046
DO - 10.1002/ps.6046
M3 - Article
VL - 77
SP - 492
EP - 501
JO - Pest Management Science
JF - Pest Management Science
IS - 1
ER -