Abstract
We congratulate Poston and colleagues1 on completion of UPBEAT, a meticulous randomised controlled trial. Unfortunately, their combined healthy eating and physical activity intervention, as with the older LIMIT trial, 2 did not prevent gestational diabetes compared with standard antenatal care. We subsequently published the DALI Lifestyle Pilot3 showing that women in our healthy eating intervention gained less weight (–2•6 kg [95% CI –4•9 to –0•2]), with a greater decrease in fasting glucose (–0•3 mmol/L [–0•4 to –0•1]) and a non-significant 33% reduction in gestational diabetes, compared with the physical activity intervention (odds ratio 0•67 [95% CI 0•25; 1•75; p=0•41]). On July 29, another randomised controlled trial4 of a healthy eating and physical activity intervention (RADIEL) reported a 39% (2–60) reduction in gestational diabetes, although this result was only significant after adjustment for baseline data (which were similar between groups).
Original language | English |
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Pages (from-to) | 761-761 |
Number of pages | 1 |
Journal | Lancet Diabetes and Endocrinology |
Volume | 3 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2015 |
Keywords
- diabetes in pregnancy
- insulin
- prenatal care