Abstract
The separation of n = 2-5 n-butyloligostyrenes has been illustrated by reversed-phase reversed-phase (RP-RP) coupled-column liquid chromatography. The coupled-column separation has been achieved by use of a C 18 column with methanol as the mobile phase followed by a DiamondBond C 18 column with acetonitrile (ACN) mobile phase. The DiamondBond C 18 is a hybrid carbon clad zirconia (CCZ)-C 18 stationary phase. Unlike a C 18-carbon clad zirconia two-dimensional liquid chromatographic system, which is orthogonal, the C 18 and DiamondBond C 18 columns combination exhibit correlations based upon the molecular weight of n-butyloligostyrenes. Using an alternative strategy to two-dimensional liquid chromatography, the molecular weight dependence displayed by both the C 18 column and DiamondBond C 18 has been used to increase throughput or decrease analysis time in the analysis of the n- butyloligostyrenes. However, this is at the expense of a portion of the two-dimensional peak capacity displayed by the C 18-carbon clad zirconia system.
| Original language | English |
|---|---|
| Pages (from-to) | 3-9 |
| Number of pages | 7 |
| Journal | Journal of Chromatography A |
| Volume | 1073 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 6 May 2005 |
Keywords
- Chromatographic analysis
- Liquid chromatography
- Multidimensional chromatography
- Oligostyrene
- Separation (Technology)
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