Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

Bin Wang, Shanmugarajah Rajendra, Darren Pavey, Prateek Sharma, Neil Merrett, Xiaojuan Wu, Elizabeth T. Snow, Vivek Kumbhari, Madeleine J. Ball, Iain K. Robertson

    Research output: Contribution to journalArticlepeer-review

    23 Citations (Scopus)

    Abstract

    To the Editor: Recently we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ’ s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1).To further clarify the role of hr-HPV infection in the Barrett ’ s metaplasia– dysplasia–adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 orhr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.
    Original languageEnglish
    Pages (from-to)1814-1816
    Number of pages3
    JournalAmerican Journal of Gastroenterology
    Volume108
    Issue number11
    DOIs
    Publication statusPublished - 2013

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