Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

Bin Wang; Shanmugarajah Rajendra; Darren Pavey; Prateek Sharma; Neil Merrett; Xiaojuan Wu; Elizabeth T. Snow; Vivek Kumbhari; Madeleine J. Ball; Iain K. Robertson

doi:10.1038/ajg.2013.206

Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

Bin Wang, Shanmugarajah Rajendra, Darren Pavey, Prateek Sharma, Neil Merrett, Xiaojuan Wu, Elizabeth T. Snow, Vivek Kumbhari, Madeleine J. Ball, Iain K. Robertson

School of Medicine

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

To the Editor: Recently we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ' s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1).To further clarify the role of hr-HPV infection in the Barrett ' s metaplasia- dysplasia-adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 orhr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.

Original language	English
Pages (from-to)	1814-1816
Number of pages	3
Journal	American Journal of Gastroenterology
Volume	108
Issue number	11
DOIs	https://doi.org/10.1038/ajg.2013.206
Publication status	Published - 2013

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title = "Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence",

abstract = "To the Editor: Recently we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ' s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1).To further clarify the role of hr-HPV infection in the Barrett ' s metaplasia- dysplasia-adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 orhr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.",

author = "Bin Wang and Shanmugarajah Rajendra and Darren Pavey and Prateek Sharma and Neil Merrett and Xiaojuan Wu and Snow, {Elizabeth T.} and Vivek Kumbhari and Ball, {Madeleine J.} and Robertson, {Iain K.}",

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doi = "10.1038/ajg.2013.206",

language = "English",

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T1 - Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

AU - Wang, Bin

AU - Rajendra, Shanmugarajah

AU - Pavey, Darren

AU - Sharma, Prateek

AU - Merrett, Neil

AU - Wu, Xiaojuan

AU - Snow, Elizabeth T.

AU - Kumbhari, Vivek

AU - Ball, Madeleine J.

AU - Robertson, Iain K.

PY - 2013

Y1 - 2013

N2 - To the Editor: Recently we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ' s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1).To further clarify the role of hr-HPV infection in the Barrett ' s metaplasia- dysplasia-adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 orhr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.

AB - To the Editor: Recently we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ' s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1).To further clarify the role of hr-HPV infection in the Barrett ' s metaplasia- dysplasia-adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 orhr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.

UR - http://handle.uws.edu.au:8081/1959.7/538085

U2 - 10.1038/ajg.2013.206

DO - 10.1038/ajg.2013.206

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SN - 0002-9270

VL - 108

SP - 1814

EP - 1816

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

IS - 11

ER -

Viral load and integration status of high-risk human papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

Abstract

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