Working-memory impairment in schizophrenia and schizotypal personality disorder

Ahmed A. Moustafa; Shadi Gray; Alejandro Morris; Glessia Matar; Anchal Garg; Ahmed Helal; Alaa Eldin A. Ayoub; Eid Abo Hamza

doi:10.1016/B978-0-12-820005-6.00007-4

Working-memory impairment in schizophrenia and schizotypal personality disorder

Ahmed A. Moustafa, Shadi Gray, Alejandro Morris, Glessia Matar, Anchal Garg, Ahmed Helal, Alaa Eldin A. Ayoub, Eid Abo Hamza

Western Sydney University

Research output: Chapter in Book / Conference Paper › Chapter

Abstract

![CDATA[Working memory (WM) refers to the temporary maintenance, updating, and manipulation of information. It is a key component in cognitive neuroscience research as it improves our understanding of cognitive operations such as comprehension, problem-solving, and planning. Impairment in WM can impact day-to-day functioning and its severity can predict long-term outcome in psychosis-spectrum disorders such as schizophrenia. The goal of this chapter is to review prior studies on WM disturbances in schizophrenia and schizotypal personality disorder using N-Back Paradigm and AX-Continuous Performance Test, two commonly used WM measures for clinical trials. In addition, the commonalities and differences in WM impairment patterns between both groups are discussed. Last, we provide summary of the gaps and limitations of previous studies which will then become the focus of future research.]]

Original language	English
Title of host publication	Cognitive and Behavioral Dysfunction in Schizophrenia
Editors	Ahmed Moustafa
Place of Publication	U.K.
Publisher	Academic Press
Pages	19-48
Number of pages	30
ISBN (Print)	9780128200056
DOIs	https://doi.org/10.1016/B978-0-12-820005-6.00007-4
Publication status	Published - 2021

Access to Document

10.1016/B978-0-12-820005-6.00007-4

Cite this

@inbook{b297a5ff77b54887990152cc104ff90e,

title = "Working-memory impairment in schizophrenia and schizotypal personality disorder",

abstract = "![CDATA[Working memory (WM) refers to the temporary maintenance, updating, and manipulation of information. It is a key component in cognitive neuroscience research as it improves our understanding of cognitive operations such as comprehension, problem-solving, and planning. Impairment in WM can impact day-to-day functioning and its severity can predict long-term outcome in psychosis-spectrum disorders such as schizophrenia. The goal of this chapter is to review prior studies on WM disturbances in schizophrenia and schizotypal personality disorder using N-Back Paradigm and AX-Continuous Performance Test, two commonly used WM measures for clinical trials. In addition, the commonalities and differences in WM impairment patterns between both groups are discussed. Last, we provide summary of the gaps and limitations of previous studies which will then become the focus of future research.]]",

author = "Moustafa, {Ahmed A.} and Shadi Gray and Alejandro Morris and Glessia Matar and Anchal Garg and Ahmed Helal and Ayoub, {Alaa Eldin A.} and Hamza, {Eid Abo}",

year = "2021",

doi = "10.1016/B978-0-12-820005-6.00007-4",

language = "English",

isbn = "9780128200056",

pages = "19--48",

editor = "Ahmed Moustafa",

booktitle = "Cognitive and Behavioral Dysfunction in Schizophrenia",

publisher = "Academic Press",

address = "United States",

}

TY - CHAP

T1 - Working-memory impairment in schizophrenia and schizotypal personality disorder

AU - Moustafa, Ahmed A.

AU - Gray, Shadi

AU - Morris, Alejandro

AU - Matar, Glessia

AU - Garg, Anchal

AU - Helal, Ahmed

AU - Ayoub, Alaa Eldin A.

AU - Hamza, Eid Abo

PY - 2021

Y1 - 2021

N2 - ![CDATA[Working memory (WM) refers to the temporary maintenance, updating, and manipulation of information. It is a key component in cognitive neuroscience research as it improves our understanding of cognitive operations such as comprehension, problem-solving, and planning. Impairment in WM can impact day-to-day functioning and its severity can predict long-term outcome in psychosis-spectrum disorders such as schizophrenia. The goal of this chapter is to review prior studies on WM disturbances in schizophrenia and schizotypal personality disorder using N-Back Paradigm and AX-Continuous Performance Test, two commonly used WM measures for clinical trials. In addition, the commonalities and differences in WM impairment patterns between both groups are discussed. Last, we provide summary of the gaps and limitations of previous studies which will then become the focus of future research.]]

AB - ![CDATA[Working memory (WM) refers to the temporary maintenance, updating, and manipulation of information. It is a key component in cognitive neuroscience research as it improves our understanding of cognitive operations such as comprehension, problem-solving, and planning. Impairment in WM can impact day-to-day functioning and its severity can predict long-term outcome in psychosis-spectrum disorders such as schizophrenia. The goal of this chapter is to review prior studies on WM disturbances in schizophrenia and schizotypal personality disorder using N-Back Paradigm and AX-Continuous Performance Test, two commonly used WM measures for clinical trials. In addition, the commonalities and differences in WM impairment patterns between both groups are discussed. Last, we provide summary of the gaps and limitations of previous studies which will then become the focus of future research.]]

UR - https://hdl.handle.net/1959.7/uws:61582

U2 - 10.1016/B978-0-12-820005-6.00007-4

DO - 10.1016/B978-0-12-820005-6.00007-4

M3 - Chapter

SN - 9780128200056

SP - 19

EP - 48

BT - Cognitive and Behavioral Dysfunction in Schizophrenia

A2 - Moustafa, Ahmed

PB - Academic Press

CY - U.K.

ER -

Working-memory impairment in schizophrenia and schizotypal personality disorder

Abstract

Access to Document

Other files and links

Fingerprint

Cite this