A review of the development of a synthetic corneal onlay for refractive correction

Margaret D.M. Evans, Keith M. McLean, Timothy C. Hughes, Deborah F. Sweeney

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

A synthetic corneal onlay, or implantable contact lens, could obviate the need for spectacles or conventional contact lenses in patients who seek convenient, reversible correction of refractive error. Several research groups have attempted to develop such a product in the past but much of the data from these studies remains unpublished due to commercial interests. This article reviews relevant papers and patents in the corneal implant field and discusses our efforts to develop a synthetic corneal onlay using a perfluoropolyether-based polymer.
Original languageEnglish
Pages (from-to)3319-3328
Number of pages10
JournalBiomaterials
Volume22
Issue number24
DOIs
Publication statusPublished - 2001
Externally publishedYes

Keywords

  • Biocompatible
  • Collagen
  • Corneal onlay
  • Epithelium
  • Fluoropolymer
  • In vivo

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